CSIR CIMAP AROMA | Compound Details

Carbolic acid Details

: IUPAC Name

Phenol

:Chemical Class

:CAS Registry Number

108-95-2

:Description

:Fragrance Type

sweet, tarry

Physical and Chemical properties

PUBCHEM ID	996
Molecular Weight (g/mol)	94.114
Molecular Formula	C6H6O
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	2
IUPAC Name	Phenol
Canonical SMILES	Oc1ccccc1
PUBCHEM IUPAC INCHIKEY	ISWSIDIOOBJBQZ-UHFFFAOYSA-N
Solubility Level	4
Vapour Pressure	-0.419

Absorption and Metabolism information

XLOGP3 AA	NA
CACTVS TPSA	20.23
BBB Level	1
Absorption Level	0
EXT PPB#Prediction	0
AlogP98	1.588
EXT CYP2D6#Prediction	0

Toxicological Information

Mouse Female FDA	Multi-Carcinogen
Mouse Male FDA	Multi-Carcinogen
Rat Female FDA	Multi-Carcinogen
Rat Male FDA	Multi-Carcinogen
Ames Prediction	Non-Mutagen
Developmental / Reproductive Toxicity	Toxic
Rat Oral LD50	0.641516
Ocular Irritancy	Severe
Hepatotoxic#Prediction	1
Effected Human Genes	NA

Ecological Information

Aerobic Biodegradability Prediction	Non-Degradable

Hazard(s) Identification

Physical hazards	not classified
Health hazards	Mild
Environmental hazards	not classified

About Table Headings

Compound Biological Activity

Serial No.	Cas No	Gene Symbol	Organism	Interaction	Interaction Actions	PubMed Id
1	108-95-2	ESR1	Homo sapiens	5-octylphenol binds to ESR1 protein	affects^binding	11518614
2	108-95-2	ESR2	Homo sapiens	5-octylphenol binds to ESR2 protein	affects^binding	11518614
3	108-95-2	ACOT2	Homo sapiens	Phenol results in decreased expression of ACOT2 mRNA	decreases^expression	17547211
4	108-95-2	AFP	Homo sapiens	Phenol results in increased expression of AFP protein	increases^expression	16966304
5	108-95-2	AKR1B10	Homo sapiens	Phenol results in increased expression of AKR1B10 mRNA	increases^expression	26198647
6	108-95-2	ALAS2	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of ALAS2 mRNA]	decreases^reaction\|increases^expression	23973255
7	108-95-2	ALB	Bos taurus	Phenol inhibits the reaction [ANFT binds to ALB protein]	affects^binding\|decreases^reaction	2121382
8	108-95-2	ALB	Homo sapiens	Phenol binds to ALB protein	affects^binding	11334365
9	108-95-2	ALPL	Homo sapiens	Phenol results in increased expression of ALPL mRNA	increases^expression	22083529
10	108-95-2	BAMBI	Homo sapiens	Phenol results in increased expression of BAMBI mRNA	increases^expression	17547211
11	108-95-2	BHLHE40	Homo sapiens	Phenol results in increased expression of BHLHE40 mRNA	increases^expression	17547211
12	108-95-2	BLCAP	Homo sapiens	Phenol results in decreased expression of BLCAP mRNA	decreases^expression	17547211
13	108-95-2	CALCA	Rattus norvegicus	Capsaicin promotes the reaction [Phenol results in decreased expression of CALCA protein]	decreases^expression\|increases^reaction	15120475
14	108-95-2	CALCA	Rattus norvegicus	Phenol results in decreased expression of CALCA mRNA	decreases^expression	15120475
15	108-95-2	CALCA	Rattus norvegicus	Phenol results in decreased expression of CALCA protein	decreases^expression	15120475
16	108-95-2	CALCB	Rattus norvegicus	Phenol results in decreased expression of CALCB mRNA	decreases^expression	15120475
17	108-95-2	CALU	Homo sapiens	Phenol results in decreased expression of CALU mRNA	decreases^expression	17547211
18	108-95-2	CASP3	Homo sapiens	Phenol results in increased activity of CASP3 protein	increases^activity	23776099
19	108-95-2	CASP8	Homo sapiens	Phenol results in increased activity of CASP8 protein	increases^activity	23776099
20	108-95-2	CASP9	Homo sapiens	Phenol results in increased activity of CASP9 protein	increases^activity	23776099
21	108-95-2	CCL2	Homo sapiens	Phenol results in increased expression of CCL2 mRNA	increases^expression	21907259
22	108-95-2	CCNA2	Homo sapiens	Phenol results in decreased expression of CCNA2 protein	decreases^expression	19293009
23	108-95-2	CHST3	Homo sapiens	Phenol results in increased expression of CHST3 mRNA	increases^expression	17547211
24	108-95-2	COL1A1	Homo sapiens	Phenol results in increased expression of COL1A1 mRNA	increases^expression	22083529
25	108-95-2	CREB1	Homo sapiens	Phenol results in increased expression of CREB1 mRNA	increases^expression	20385217
26	108-95-2	CROP	Homo sapiens	Phenol results in decreased expression of CROP mRNA	decreases^expression	17547211
27	108-95-2	CRP	Catla catla	Phenol results in increased expression of CRP protein	increases^expression	12151716
28	108-95-2	CXCL8	Homo sapiens	IL1A protein affects the reaction [Phenol results in increased expression of CXCL8 protein]	affects^reaction\|increases^expression	8006454
29	108-95-2	CXCL8	Homo sapiens	Phenol results in increased expression of CXCL8 mRNA	increases^expression	8006454
30	108-95-2	CXCL8	Homo sapiens	Phenol results in increased expression of CXCL8 protein	increases^expression	8006454
31	108-95-2	CXCL8	Homo sapiens	TNF protein affects the reaction [Phenol results in increased expression of CXCL8 protein]	affects^reaction\|increases^expression	8006454
32	108-95-2	CYBA	Rattus norvegicus	Phenol results in increased expression of CYBA mRNA	increases^expression	16785328
33	108-95-2	CYBB	Rattus norvegicus	Phenol results in increased expression of CYBB mRNA	increases^expression	16785328
34	108-95-2	CYP19A1	Cyprinus carpio	Phenol inhibits the reaction [LHB protein results in increased expression of CYP19A1 mRNA]	decreases^reaction\|increases^expression	23423282
35	108-95-2	CYP1A1	Homo sapiens	CYP1A1 protein affects the susceptibility to Phenol	affects^response to substance	8242868
36	108-95-2	CYP1A2	Homo sapiens	CYP1A2 protein affects the susceptibility to Phenol	affects^response to substance	8242868
37	108-95-2	CYP2E1	Rattus norvegicus	[Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]	affects^binding\|affects^cotreatment\|increases^chemical synthesis\|increases^metabolic processing	8211999
38	108-95-2	CYP4F3	Homo sapiens	Phenol results in increased expression of CYP4F3 mRNA	increases^expression	19029204\|20036648
39	108-95-2	CYP4F3	Homo sapiens	Phenol results in increased expression of CYP4F3 protein	increases^expression	19029204\|20036648
40	108-95-2	DAZAP1	Homo sapiens	Phenol results in increased expression of DAZAP1 mRNA	increases^expression	17547211
41	108-95-2	DCP1A	Homo sapiens	Phenol results in increased expression of DCP1A mRNA	increases^expression	17547211
42	108-95-2	DDX3X	Homo sapiens	Phenol results in decreased expression of DDX3X mRNA	decreases^expression	17547211
43	108-95-2	DUSP1	Homo sapiens	Phenol results in increased expression of DUSP1 mRNA	increases^expression	17547211
44	108-95-2	ELL2	Homo sapiens	Phenol results in increased expression of ELL2 mRNA	increases^expression	17547211
45	108-95-2	ESR1	Homo sapiens	Phenol results in increased expression of ESR1 mRNA	increases^expression	22083529
46	108-95-2	ESR1		Phenol analog affects the reaction [ESR1 protein binds to NCOA2 protein]	affects^binding\|affects^reaction	16546889
47	108-95-2	ESR1		Phenol metabolite affects the reaction [ESR1 protein binds to NCOA2 protein]	affects^binding\|affects^reaction	16546889
48	108-95-2	ETS2	Homo sapiens	Phenol results in increased expression of ETS2 mRNA	increases^expression	17547211
49	108-95-2	FAS	Homo sapiens	Phenol results in increased expression of FAS mRNA	increases^expression	17547211
50	108-95-2	FAS	Homo sapiens	Phenol results in increased expression of FAS protein	increases^expression	23776099
51	108-95-2	FASLG	Homo sapiens	Phenol results in increased expression of FASLG protein	increases^expression	23776099
52	108-95-2	FBXW2	Homo sapiens	Phenol results in decreased expression of FBXW2 mRNA	decreases^expression	17547211
53	108-95-2	FOSL1	Homo sapiens	Phenol results in increased expression of FOSL1 mRNA	increases^expression	17547211
54	108-95-2	GATA1	Homo sapiens	decitabine inhibits the reaction [Phenol inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]	decreases^reaction\|increases^expression	23973255
55	108-95-2	GATA1	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]	decreases^reaction\|increases^expression	21414390\|23973255
56	108-95-2	GATA2	Homo sapiens	Phenol promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]	decreases^expression\|increases^reaction	21414390
57	108-95-2	GATA2	Homo sapiens	Phenol results in decreased expression of GATA2 mRNA	decreases^expression	21414390
58	108-95-2	GCLC	Homo sapiens	Phenol results in increased expression of GCLC mRNA	increases^expression	26198647
59	108-95-2	GCLM	Homo sapiens	Phenol results in increased expression of GCLM mRNA	increases^expression	26198647
60	108-95-2	GJA1	Rattus norvegicus	Phenol results in increased expression of GJA1 mRNA	increases^expression	15094358
61	108-95-2	GJA1	Rattus norvegicus	Phenol results in increased expression of GJA1 protein	increases^expression	15094358
62	108-95-2	GPAT3	Homo sapiens	Phenol results in increased expression of GPAT3 mRNA	increases^expression	26198647
63	108-95-2	GSTD4	Drosophila melanogaster	Phenol results in decreased expression of GSTD4 mRNA	decreases^expression	16161104
64	108-95-2	GSTD7	Drosophila melanogaster	Phenol results in decreased expression of GSTD7 mRNA	decreases^expression	16161104
65	108-95-2	GTF3C4	Homo sapiens	Phenol results in increased expression of GTF3C4 mRNA	increases^expression	17547211
66	108-95-2	HAVCR1	Homo sapiens	Phenol results in increased expression of HAVCR1 mRNA	increases^expression	21907259
67	108-95-2	HBB	Homo sapiens	decitabine inhibits the reaction [Phenol inhibits the reaction [Hemin results in increased expression of HBB mRNA]]	decreases^reaction\|increases^expression	23973255
68	108-95-2	HBB	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of HBB mRNA]	decreases^reaction\|increases^expression	21414390\|23973255
69	108-95-2	HES1	Homo sapiens	Phenol results in increased expression of HES1 mRNA	increases^expression	17547211
70	108-95-2	HMBS	Homo sapiens	decitabine inhibits the reaction [Phenol inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]	decreases^reaction\|increases^expression	23973255
71	108-95-2	HMBS	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of HMBS mRNA]	decreases^reaction\|increases^expression	21414390\|23973255
72	108-95-2	HMOX1	Homo sapiens	Phenol results in increased expression of HMOX1 mRNA	increases^expression	17547211
73	108-95-2	HNRNPH2	Homo sapiens	Phenol results in decreased expression of HNRNPH2 mRNA	decreases^expression	17547211
74	108-95-2	ID3	Homo sapiens	Phenol results in increased expression of ID3 mRNA	increases^expression	17547211
75	108-95-2	IL1A	Homo sapiens	Phenol results in increased expression of IL1A mRNA	increases^expression	8006454
76	108-95-2	IL1A	Homo sapiens	Phenol results in increased expression of IL1A protein	increases^expression	8006454
77	108-95-2	IL1B	Homo sapiens	Phenol results in increased expression of IL1B mRNA	increases^expression	8006454
78	108-95-2	IL1B	Rattus norvegicus	Phenol results in decreased expression of IL1B	decreases^expression	12160195
79	108-95-2	IL1B	Rattus norvegicus	tempol inhibits the reaction [Phenol results in decreased expression of IL1B mRNA]	decreases^expression\|decreases^reaction	16785328
80	108-95-2	IL6	Mus musculus	Phenol results in decreased expression of IL6 mRNA	decreases^expression	12819374
81	108-95-2	ING3	Homo sapiens	Phenol results in increased expression of ING3 mRNA	increases^expression	17547211
82	108-95-2	KLF10	Homo sapiens	Phenol results in increased expression of KLF10 mRNA	increases^expression	17547211
83	108-95-2	KLF6	Homo sapiens	Phenol results in increased expression of KLF6 mRNA	increases^expression	17547211
84	108-95-2	KPNA4	Homo sapiens	Phenol results in increased expression of KPNA4 mRNA	increases^expression	17547211
85	108-95-2	LHB	Cyprinus carpio	Phenol inhibits the reaction [LHB protein results in increased expression of NR5A1 protein]	decreases^reaction\|increases^expression	23423282
86	108-95-2	LRP5	Homo sapiens	Phenol results in increased expression of LRP5 mRNA	increases^expression	17547211
87	108-95-2	MAN1A2	Homo sapiens	Phenol results in decreased expression of MAN1A2 mRNA	decreases^expression	17547211
88	108-95-2	MCL1	Homo sapiens	Phenol results in decreased expression of MCL1 mRNA	decreases^expression	17547211
89	108-95-2	MGAT2	Homo sapiens	Phenol results in decreased expression of MGAT2 mRNA	decreases^expression	17547211
90	108-95-2	MPO		Phenol binds to MPO protein	affects^binding	8132563
91	108-95-2	MRPL49	Homo sapiens	Phenol results in decreased expression of MRPL49 mRNA	decreases^expression	17547211
92	108-95-2	MT1H	Homo sapiens	Phenol results in decreased expression of MT1H mRNA	decreases^expression	17547211
93	108-95-2	MT1X	Homo sapiens	Phenol results in decreased expression of MT1X mRNA	decreases^expression	17547211
94	108-95-2	MYB	Gallus gallus	Phenol results in decreased activity of MYB protein	decreases^activity	15541759
95	108-95-2	MYC	Homo sapiens	Phenol results in increased expression of MYC mRNA	increases^expression	17547211
96	108-95-2	NCF1	Rattus norvegicus	Phenol results in increased expression of NCF1 mRNA	increases^expression	16785328
97	108-95-2	NFE2	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of NFE2 mRNA]	decreases^reaction\|increases^expression	21414390
98	108-95-2	NFKB1	Homo sapiens	Phenol results in increased expression of NFKB1 mRNA	increases^expression	20385217
99	108-95-2	NFYA	Homo sapiens	Phenol results in increased expression of NFYA mRNA	increases^expression	17547211
100	108-95-2	NOS1	Rattus norvegicus	Phenol results in decreased expression of NOS1	decreases^expression	12160195
101	108-95-2	NOS1	Rattus norvegicus	tempol inhibits the reaction [Phenol results in decreased expression of NOS1 mRNA]	decreases^expression\|decreases^reaction	16785328
102	108-95-2	NOX3	Rattus norvegicus	Phenol results in increased expression of NOX3 mRNA	increases^expression	16785328
103	108-95-2	NQO1	Homo sapiens	Phenol results in increased activity of NQO1 protein	increases^activity	9029048
104	108-95-2	NQO1	Homo sapiens	Phenol results in increased expression of NQO1 mRNA	increases^expression	9029048
105	108-95-2	NR0B2	Homo sapiens	Phenol results in decreased expression of NR0B2 mRNA	decreases^expression	17547211
106	108-95-2	PELI1	Homo sapiens	Phenol results in increased expression of PELI1 mRNA	increases^expression	17547211
107	108-95-2	PER2	Homo sapiens	Phenol results in increased expression of PER2 mRNA	increases^expression	17547211
108	108-95-2	PIK3CD	Homo sapiens	Phenol results in increased expression of PIK3CD mRNA	increases^expression	17547211
109	108-95-2	PIM1	Homo sapiens	Phenol results in increased expression of PIM1 mRNA	increases^expression	17547211
110	108-95-2	PNMA1	Homo sapiens	Phenol results in decreased expression of PNMA1 mRNA	decreases^expression	17547211
111	108-95-2	PNN	Homo sapiens	Phenol results in decreased expression of PNN mRNA	decreases^expression	17547211
112	108-95-2	PPARG	Homo sapiens	Phenol results in increased expression of PPARG mRNA	increases^expression	17547211
113	108-95-2	PPM1D	Homo sapiens	Phenol results in increased expression of PPM1D mRNA	increases^expression	17547211
114	108-95-2	PRKDC	Homo sapiens	Phenol results in increased expression of PRKDC	increases^expression	20036648
115	108-95-2	PRKDC	Homo sapiens	Phenol results in increased expression of PRKDC mRNA	increases^expression	20096274
116	108-95-2	PRKDC	Homo sapiens	Phenol results in increased expression of PRKDC protein	increases^expression	20096274
117	108-95-2	PSA	Homo sapiens	Phenol results in increased expression of PSA protein	increases^expression	16966304
118	108-95-2	RAB9A	Homo sapiens	Phenol results in decreased expression of RAB9A mRNA	decreases^expression	17547211
119	108-95-2	REPIN1	Homo sapiens	Phenol results in decreased expression of REPIN1 mRNA	decreases^expression	17547211
120	108-95-2	RRAGA	Homo sapiens	Phenol results in decreased expression of RRAGA mRNA	decreases^expression	17547211
121	108-95-2	SCAND1	Homo sapiens	Phenol results in decreased expression of SCAND1 mRNA	decreases^expression	17547211
122	108-95-2	SEPHS2	Homo sapiens	Phenol results in decreased expression of SEPHS2 mRNA	decreases^expression	17547211
123	108-95-2	SIK1	Homo sapiens	Phenol results in increased expression of SIK1 mRNA	increases^expression	17547211
124	108-95-2	SIRT1	Homo sapiens	Phenol results in increased expression of SIRT1 mRNA	increases^expression	17547211
125	108-95-2	SLC12A6	Homo sapiens	Phenol results in increased expression of SLC12A6 mRNA	increases^expression	17547211
126	108-95-2	SLC7A11	Homo sapiens	Phenol results in increased expression of SLC7A11 mRNA	increases^expression	26198647
127	108-95-2	SQSTM1	Homo sapiens	Phenol results in increased expression of SQSTM1 mRNA	increases^expression	26198647
128	108-95-2	SRSF1	Homo sapiens	Phenol results in decreased expression of SRSF1 mRNA	decreases^expression	17547211
129	108-95-2	SRSF5	Homo sapiens	Phenol results in decreased expression of SRSF5 mRNA	decreases^expression	17547211
130	108-95-2	SRXN1	Homo sapiens	Phenol results in increased expression of SRXN1 mRNA	increases^expression	26198647
131	108-95-2	SS18L2	Homo sapiens	Phenol results in decreased expression of SS18L2 mRNA	decreases^expression	17547211
132	108-95-2	TAF7	Homo sapiens	Phenol results in decreased expression of TAF7 mRNA	decreases^expression	17547211
133	108-95-2	TARDBP	Homo sapiens	Phenol results in decreased expression of TARDBP mRNA	decreases^expression	17547211
134	108-95-2	TCFL5	Homo sapiens	Phenol results in increased expression of TCFL5 mRNA	increases^expression	17547211
135	108-95-2	TERF2	Homo sapiens	Phenol results in increased expression of TERF2 mRNA	increases^expression	17547211
136	108-95-2	TFRC	Homo sapiens	Phenol promotes the reaction [Hemin results in decreased expression of TFRC mRNA]	decreases^expression\|increases^reaction	21414390
137	108-95-2	TFRC	Homo sapiens	Phenol results in decreased expression of TFRC protein	decreases^expression	21414390
138	108-95-2	TGIF1	Homo sapiens	Phenol results in increased expression of TGIF1 mRNA	increases^expression	17547211
139	108-95-2	TIMM17A	Homo sapiens	Phenol results in decreased expression of TIMM17A mRNA	decreases^expression	17547211
140	108-95-2	TNF	Homo sapiens	Phenol results in increased expression of TNF mRNA	increases^expression	20385217\|8006454
141	108-95-2	TNF	Homo sapiens	Phenol results in increased expression of TNF protein	increases^expression	8006454
142	108-95-2	TNF	Mus musculus	Phenol results in decreased expression of TNF mRNA	decreases^expression	12819374
143	108-95-2	TNFAIP3	Homo sapiens	Phenol results in increased expression of TNFAIP3 mRNA	increases^expression	17547211
144	108-95-2	TNFRSF21	Homo sapiens	Phenol results in increased expression of TNFRSF21 mRNA	increases^expression	17547211
145	108-95-2	TOB1	Homo sapiens	Phenol results in decreased expression of TOB1 mRNA	decreases^expression	17547211
146	108-95-2	TRIB1	Homo sapiens	Phenol results in increased expression of TRIB1 mRNA	increases^expression	17547211
147	108-95-2	TRP53	Mus musculus	Phenol results in increased expression of TRP53 protein	increases^expression	9667752
148	108-95-2	TUFT1	Homo sapiens	Phenol results in increased expression of TUFT1 mRNA	increases^expression	17547211
149	108-95-2	TXNRD1	Homo sapiens	Phenol results in increased expression of TXNRD1 mRNA	increases^expression	17547211
150	108-95-2	UGCG	Homo sapiens	Phenol results in increased expression of UGCG mRNA	increases^expression	17547211
151	108-95-2	VNN1	Homo sapiens	Phenol results in increased expression of VNN1 mRNA	increases^expression	21907259
152	108-95-2	VRK2	Homo sapiens	Phenol results in increased expression of VRK2 mRNA	increases^expression	17547211
153	108-95-2	ESR1	Homo sapiens	5-octylphenol binds to ESR1 protein	affects^binding	11518614
154	108-95-2	ESR2	Homo sapiens	5-octylphenol binds to ESR2 protein	affects^binding	11518614
155	108-95-2	ACOT2	Homo sapiens	Phenol results in decreased expression of ACOT2 mRNA	decreases^expression	17547211
156	108-95-2	AFP	Homo sapiens	Phenol results in increased expression of AFP protein	increases^expression	16966304
157	108-95-2	AKR1B10	Homo sapiens	Phenol results in increased expression of AKR1B10 mRNA	increases^expression	26198647
158	108-95-2	ALAS2	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of ALAS2 mRNA]	decreases^reaction\|increases^expression	23973255
159	108-95-2	ALB	Bos taurus	Phenol inhibits the reaction [ANFT binds to ALB protein]	affects^binding\|decreases^reaction	2121382
160	108-95-2	ALB	Homo sapiens	Phenol binds to ALB protein	affects^binding	11334365
161	108-95-2	ALPL	Homo sapiens	Phenol results in increased expression of ALPL mRNA	increases^expression	22083529
162	108-95-2	BAMBI	Homo sapiens	Phenol results in increased expression of BAMBI mRNA	increases^expression	17547211
163	108-95-2	BHLHE40	Homo sapiens	Phenol results in increased expression of BHLHE40 mRNA	increases^expression	17547211
164	108-95-2	BLCAP	Homo sapiens	Phenol results in decreased expression of BLCAP mRNA	decreases^expression	17547211
165	108-95-2	CALCA	Rattus norvegicus	Capsaicin promotes the reaction [Phenol results in decreased expression of CALCA protein]	decreases^expression\|increases^reaction	15120475
166	108-95-2	CALCA	Rattus norvegicus	Phenol results in decreased expression of CALCA mRNA	decreases^expression	15120475
167	108-95-2	CALCA	Rattus norvegicus	Phenol results in decreased expression of CALCA protein	decreases^expression	15120475
168	108-95-2	CALCB	Rattus norvegicus	Phenol results in decreased expression of CALCB mRNA	decreases^expression	15120475
169	108-95-2	CALU	Homo sapiens	Phenol results in decreased expression of CALU mRNA	decreases^expression	17547211
170	108-95-2	CASP3	Homo sapiens	Phenol results in increased activity of CASP3 protein	increases^activity	23776099
171	108-95-2	CASP8	Homo sapiens	Phenol results in increased activity of CASP8 protein	increases^activity	23776099
172	108-95-2	CASP9	Homo sapiens	Phenol results in increased activity of CASP9 protein	increases^activity	23776099
173	108-95-2	CCL2	Homo sapiens	Phenol results in increased expression of CCL2 mRNA	increases^expression	21907259
174	108-95-2	CCNA2	Homo sapiens	Phenol results in decreased expression of CCNA2 protein	decreases^expression	19293009
175	108-95-2	CHST3	Homo sapiens	Phenol results in increased expression of CHST3 mRNA	increases^expression	17547211
176	108-95-2	COL1A1	Homo sapiens	Phenol results in increased expression of COL1A1 mRNA	increases^expression	22083529
177	108-95-2	CREB1	Homo sapiens	Phenol results in increased expression of CREB1 mRNA	increases^expression	20385217
178	108-95-2	CROP	Homo sapiens	Phenol results in decreased expression of CROP mRNA	decreases^expression	17547211
179	108-95-2	CRP	Catla catla	Phenol results in increased expression of CRP protein	increases^expression	12151716
180	108-95-2	CXCL8	Homo sapiens	IL1A protein affects the reaction [Phenol results in increased expression of CXCL8 protein]	affects^reaction\|increases^expression	8006454
181	108-95-2	CXCL8	Homo sapiens	Phenol results in increased expression of CXCL8 mRNA	increases^expression	8006454
182	108-95-2	CXCL8	Homo sapiens	Phenol results in increased expression of CXCL8 protein	increases^expression	8006454
183	108-95-2	CXCL8	Homo sapiens	TNF protein affects the reaction [Phenol results in increased expression of CXCL8 protein]	affects^reaction\|increases^expression	8006454
184	108-95-2	CYBA	Rattus norvegicus	Phenol results in increased expression of CYBA mRNA	increases^expression	16785328
185	108-95-2	CYBB	Rattus norvegicus	Phenol results in increased expression of CYBB mRNA	increases^expression	16785328
186	108-95-2	CYP19A1	Cyprinus carpio	Phenol inhibits the reaction [LHB protein results in increased expression of CYP19A1 mRNA]	decreases^reaction\|increases^expression	23423282
187	108-95-2	CYP1A1	Homo sapiens	CYP1A1 protein affects the susceptibility to Phenol	affects^response to substance	8242868
188	108-95-2	CYP1A2	Homo sapiens	CYP1A2 protein affects the susceptibility to Phenol	affects^response to substance	8242868
189	108-95-2	CYP2E1	Rattus norvegicus	[Glutathione co-treated with [CYP2E1 protein results in increased metabolism of Phenol]] results in increased chemical synthesis of [Glutathione binds to hydroquinone metabolite]	affects^binding\|affects^cotreatment\|increases^chemical synthesis\|increases^metabolic processing	8211999
190	108-95-2	CYP4F3	Homo sapiens	Phenol results in increased expression of CYP4F3 mRNA	increases^expression	19029204\|20036648
191	108-95-2	CYP4F3	Homo sapiens	Phenol results in increased expression of CYP4F3 protein	increases^expression	19029204\|20036648
192	108-95-2	DAZAP1	Homo sapiens	Phenol results in increased expression of DAZAP1 mRNA	increases^expression	17547211
193	108-95-2	DCP1A	Homo sapiens	Phenol results in increased expression of DCP1A mRNA	increases^expression	17547211
194	108-95-2	DDX3X	Homo sapiens	Phenol results in decreased expression of DDX3X mRNA	decreases^expression	17547211
195	108-95-2	DUSP1	Homo sapiens	Phenol results in increased expression of DUSP1 mRNA	increases^expression	17547211
196	108-95-2	ELL2	Homo sapiens	Phenol results in increased expression of ELL2 mRNA	increases^expression	17547211
197	108-95-2	ESR1	Homo sapiens	Phenol results in increased expression of ESR1 mRNA	increases^expression	22083529
198	108-95-2	ESR1		Phenol analog affects the reaction [ESR1 protein binds to NCOA2 protein]	affects^binding\|affects^reaction	16546889
199	108-95-2	ESR1		Phenol metabolite affects the reaction [ESR1 protein binds to NCOA2 protein]	affects^binding\|affects^reaction	16546889
200	108-95-2	ETS2	Homo sapiens	Phenol results in increased expression of ETS2 mRNA	increases^expression	17547211
201	108-95-2	FAS	Homo sapiens	Phenol results in increased expression of FAS mRNA	increases^expression	17547211
202	108-95-2	FAS	Homo sapiens	Phenol results in increased expression of FAS protein	increases^expression	23776099
203	108-95-2	FASLG	Homo sapiens	Phenol results in increased expression of FASLG protein	increases^expression	23776099
204	108-95-2	FBXW2	Homo sapiens	Phenol results in decreased expression of FBXW2 mRNA	decreases^expression	17547211
205	108-95-2	FOSL1	Homo sapiens	Phenol results in increased expression of FOSL1 mRNA	increases^expression	17547211
206	108-95-2	GATA1	Homo sapiens	decitabine inhibits the reaction [Phenol inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]]	decreases^reaction\|increases^expression	23973255
207	108-95-2	GATA1	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of GATA1 mRNA]	decreases^reaction\|increases^expression	21414390\|23973255
208	108-95-2	GATA2	Homo sapiens	Phenol promotes the reaction [Hemin results in decreased expression of GATA2 mRNA]	decreases^expression\|increases^reaction	21414390
209	108-95-2	GATA2	Homo sapiens	Phenol results in decreased expression of GATA2 mRNA	decreases^expression	21414390
210	108-95-2	GCLC	Homo sapiens	Phenol results in increased expression of GCLC mRNA	increases^expression	26198647
211	108-95-2	GCLM	Homo sapiens	Phenol results in increased expression of GCLM mRNA	increases^expression	26198647
212	108-95-2	GJA1	Rattus norvegicus	Phenol results in increased expression of GJA1 mRNA	increases^expression	15094358
213	108-95-2	GJA1	Rattus norvegicus	Phenol results in increased expression of GJA1 protein	increases^expression	15094358
214	108-95-2	GPAT3	Homo sapiens	Phenol results in increased expression of GPAT3 mRNA	increases^expression	26198647
215	108-95-2	GSTD4	Drosophila melanogaster	Phenol results in decreased expression of GSTD4 mRNA	decreases^expression	16161104
216	108-95-2	GSTD7	Drosophila melanogaster	Phenol results in decreased expression of GSTD7 mRNA	decreases^expression	16161104
217	108-95-2	GTF3C4	Homo sapiens	Phenol results in increased expression of GTF3C4 mRNA	increases^expression	17547211
218	108-95-2	HAVCR1	Homo sapiens	Phenol results in increased expression of HAVCR1 mRNA	increases^expression	21907259
219	108-95-2	HBB	Homo sapiens	decitabine inhibits the reaction [Phenol inhibits the reaction [Hemin results in increased expression of HBB mRNA]]	decreases^reaction\|increases^expression	23973255
220	108-95-2	HBB	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of HBB mRNA]	decreases^reaction\|increases^expression	21414390\|23973255
221	108-95-2	HES1	Homo sapiens	Phenol results in increased expression of HES1 mRNA	increases^expression	17547211
222	108-95-2	HMBS	Homo sapiens	decitabine inhibits the reaction [Phenol inhibits the reaction [Hemin results in increased expression of HMBS mRNA]]	decreases^reaction\|increases^expression	23973255
223	108-95-2	HMBS	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of HMBS mRNA]	decreases^reaction\|increases^expression	21414390\|23973255
224	108-95-2	HMOX1	Homo sapiens	Phenol results in increased expression of HMOX1 mRNA	increases^expression	17547211
225	108-95-2	HNRNPH2	Homo sapiens	Phenol results in decreased expression of HNRNPH2 mRNA	decreases^expression	17547211
226	108-95-2	ID3	Homo sapiens	Phenol results in increased expression of ID3 mRNA	increases^expression	17547211
227	108-95-2	IL1A	Homo sapiens	Phenol results in increased expression of IL1A mRNA	increases^expression	8006454
228	108-95-2	IL1A	Homo sapiens	Phenol results in increased expression of IL1A protein	increases^expression	8006454
229	108-95-2	IL1B	Homo sapiens	Phenol results in increased expression of IL1B mRNA	increases^expression	8006454
230	108-95-2	IL1B	Rattus norvegicus	Phenol results in decreased expression of IL1B	decreases^expression	12160195
231	108-95-2	IL1B	Rattus norvegicus	tempol inhibits the reaction [Phenol results in decreased expression of IL1B mRNA]	decreases^expression\|decreases^reaction	16785328
232	108-95-2	IL6	Mus musculus	Phenol results in decreased expression of IL6 mRNA	decreases^expression	12819374
233	108-95-2	ING3	Homo sapiens	Phenol results in increased expression of ING3 mRNA	increases^expression	17547211
234	108-95-2	KLF10	Homo sapiens	Phenol results in increased expression of KLF10 mRNA	increases^expression	17547211
235	108-95-2	KLF6	Homo sapiens	Phenol results in increased expression of KLF6 mRNA	increases^expression	17547211
236	108-95-2	KPNA4	Homo sapiens	Phenol results in increased expression of KPNA4 mRNA	increases^expression	17547211
237	108-95-2	LHB	Cyprinus carpio	Phenol inhibits the reaction [LHB protein results in increased expression of NR5A1 protein]	decreases^reaction\|increases^expression	23423282
238	108-95-2	LRP5	Homo sapiens	Phenol results in increased expression of LRP5 mRNA	increases^expression	17547211
239	108-95-2	MAN1A2	Homo sapiens	Phenol results in decreased expression of MAN1A2 mRNA	decreases^expression	17547211
240	108-95-2	MCL1	Homo sapiens	Phenol results in decreased expression of MCL1 mRNA	decreases^expression	17547211
241	108-95-2	MGAT2	Homo sapiens	Phenol results in decreased expression of MGAT2 mRNA	decreases^expression	17547211
242	108-95-2	MPO		Phenol binds to MPO protein	affects^binding	8132563
243	108-95-2	MRPL49	Homo sapiens	Phenol results in decreased expression of MRPL49 mRNA	decreases^expression	17547211
244	108-95-2	MT1H	Homo sapiens	Phenol results in decreased expression of MT1H mRNA	decreases^expression	17547211
245	108-95-2	MT1X	Homo sapiens	Phenol results in decreased expression of MT1X mRNA	decreases^expression	17547211
246	108-95-2	MYB	Gallus gallus	Phenol results in decreased activity of MYB protein	decreases^activity	15541759
247	108-95-2	MYC	Homo sapiens	Phenol results in increased expression of MYC mRNA	increases^expression	17547211
248	108-95-2	NCF1	Rattus norvegicus	Phenol results in increased expression of NCF1 mRNA	increases^expression	16785328
249	108-95-2	NFE2	Homo sapiens	Phenol inhibits the reaction [Hemin results in increased expression of NFE2 mRNA]	decreases^reaction\|increases^expression	21414390
250	108-95-2	NFKB1	Homo sapiens	Phenol results in increased expression of NFKB1 mRNA	increases^expression	20385217
251	108-95-2	NFYA	Homo sapiens	Phenol results in increased expression of NFYA mRNA	increases^expression	17547211
252	108-95-2	NOS1	Rattus norvegicus	Phenol results in decreased expression of NOS1	decreases^expression	12160195
253	108-95-2	NOS1	Rattus norvegicus	tempol inhibits the reaction [Phenol results in decreased expression of NOS1 mRNA]	decreases^expression\|decreases^reaction	16785328
254	108-95-2	NOX3	Rattus norvegicus	Phenol results in increased expression of NOX3 mRNA	increases^expression	16785328
255	108-95-2	NQO1	Homo sapiens	Phenol results in increased activity of NQO1 protein	increases^activity	9029048
256	108-95-2	NQO1	Homo sapiens	Phenol results in increased expression of NQO1 mRNA	increases^expression	9029048
257	108-95-2	NR0B2	Homo sapiens	Phenol results in decreased expression of NR0B2 mRNA	decreases^expression	17547211
258	108-95-2	PELI1	Homo sapiens	Phenol results in increased expression of PELI1 mRNA	increases^expression	17547211
259	108-95-2	PER2	Homo sapiens	Phenol results in increased expression of PER2 mRNA	increases^expression	17547211
260	108-95-2	PIK3CD	Homo sapiens	Phenol results in increased expression of PIK3CD mRNA	increases^expression	17547211
261	108-95-2	PIM1	Homo sapiens	Phenol results in increased expression of PIM1 mRNA	increases^expression	17547211
262	108-95-2	PNMA1	Homo sapiens	Phenol results in decreased expression of PNMA1 mRNA	decreases^expression	17547211
263	108-95-2	PNN	Homo sapiens	Phenol results in decreased expression of PNN mRNA	decreases^expression	17547211
264	108-95-2	PPARG	Homo sapiens	Phenol results in increased expression of PPARG mRNA	increases^expression	17547211
265	108-95-2	PPM1D	Homo sapiens	Phenol results in increased expression of PPM1D mRNA	increases^expression	17547211
266	108-95-2	PRKDC	Homo sapiens	Phenol results in increased expression of PRKDC	increases^expression	20036648
267	108-95-2	PRKDC	Homo sapiens	Phenol results in increased expression of PRKDC mRNA	increases^expression	20096274
268	108-95-2	PRKDC	Homo sapiens	Phenol results in increased expression of PRKDC protein	increases^expression	20096274
269	108-95-2	PSA	Homo sapiens	Phenol results in increased expression of PSA protein	increases^expression	16966304
270	108-95-2	RAB9A	Homo sapiens	Phenol results in decreased expression of RAB9A mRNA	decreases^expression	17547211
271	108-95-2	REPIN1	Homo sapiens	Phenol results in decreased expression of REPIN1 mRNA	decreases^expression	17547211
272	108-95-2	RRAGA	Homo sapiens	Phenol results in decreased expression of RRAGA mRNA	decreases^expression	17547211
273	108-95-2	SCAND1	Homo sapiens	Phenol results in decreased expression of SCAND1 mRNA	decreases^expression	17547211
274	108-95-2	SEPHS2	Homo sapiens	Phenol results in decreased expression of SEPHS2 mRNA	decreases^expression	17547211
275	108-95-2	SIK1	Homo sapiens	Phenol results in increased expression of SIK1 mRNA	increases^expression	17547211
276	108-95-2	SIRT1	Homo sapiens	Phenol results in increased expression of SIRT1 mRNA	increases^expression	17547211
277	108-95-2	SLC12A6	Homo sapiens	Phenol results in increased expression of SLC12A6 mRNA	increases^expression	17547211
278	108-95-2	SLC7A11	Homo sapiens	Phenol results in increased expression of SLC7A11 mRNA	increases^expression	26198647
279	108-95-2	SQSTM1	Homo sapiens	Phenol results in increased expression of SQSTM1 mRNA	increases^expression	26198647
280	108-95-2	SRSF1	Homo sapiens	Phenol results in decreased expression of SRSF1 mRNA	decreases^expression	17547211
281	108-95-2	SRSF5	Homo sapiens	Phenol results in decreased expression of SRSF5 mRNA	decreases^expression	17547211
282	108-95-2	SRXN1	Homo sapiens	Phenol results in increased expression of SRXN1 mRNA	increases^expression	26198647
283	108-95-2	SS18L2	Homo sapiens	Phenol results in decreased expression of SS18L2 mRNA	decreases^expression	17547211
284	108-95-2	TAF7	Homo sapiens	Phenol results in decreased expression of TAF7 mRNA	decreases^expression	17547211
285	108-95-2	TARDBP	Homo sapiens	Phenol results in decreased expression of TARDBP mRNA	decreases^expression	17547211
286	108-95-2	TCFL5	Homo sapiens	Phenol results in increased expression of TCFL5 mRNA	increases^expression	17547211
287	108-95-2	TERF2	Homo sapiens	Phenol results in increased expression of TERF2 mRNA	increases^expression	17547211
288	108-95-2	TFRC	Homo sapiens	Phenol promotes the reaction [Hemin results in decreased expression of TFRC mRNA]	decreases^expression\|increases^reaction	21414390
289	108-95-2	TFRC	Homo sapiens	Phenol results in decreased expression of TFRC protein	decreases^expression	21414390
290	108-95-2	TGIF1	Homo sapiens	Phenol results in increased expression of TGIF1 mRNA	increases^expression	17547211
291	108-95-2	TIMM17A	Homo sapiens	Phenol results in decreased expression of TIMM17A mRNA	decreases^expression	17547211
292	108-95-2	TNF	Homo sapiens	Phenol results in increased expression of TNF mRNA	increases^expression	20385217\|8006454
293	108-95-2	TNF	Homo sapiens	Phenol results in increased expression of TNF protein	increases^expression	8006454
294	108-95-2	TNF	Mus musculus	Phenol results in decreased expression of TNF mRNA	decreases^expression	12819374
295	108-95-2	TNFAIP3	Homo sapiens	Phenol results in increased expression of TNFAIP3 mRNA	increases^expression	17547211
296	108-95-2	TNFRSF21	Homo sapiens	Phenol results in increased expression of TNFRSF21 mRNA	increases^expression	17547211
297	108-95-2	TOB1	Homo sapiens	Phenol results in decreased expression of TOB1 mRNA	decreases^expression	17547211
298	108-95-2	TRIB1	Homo sapiens	Phenol results in increased expression of TRIB1 mRNA	increases^expression	17547211
299	108-95-2	TRP53	Mus musculus	Phenol results in increased expression of TRP53 protein	increases^expression	9667752
300	108-95-2	TUFT1	Homo sapiens	Phenol results in increased expression of TUFT1 mRNA	increases^expression	17547211
301	108-95-2	TXNRD1	Homo sapiens	Phenol results in increased expression of TXNRD1 mRNA	increases^expression	17547211
302	108-95-2	UGCG	Homo sapiens	Phenol results in increased expression of UGCG mRNA	increases^expression	17547211
303	108-95-2	VNN1	Homo sapiens	Phenol results in increased expression of VNN1 mRNA	increases^expression	21907259
304	108-95-2	VRK2	Homo sapiens	Phenol results in increased expression of VRK2 mRNA	increases^expression	17547211

Serial No.	Activity Name	Details	References (PubMed)	Other details EPA (U.S)	Clinical Trials (U.S. NIH)
1				108-95-2	Carbolic acid

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