Oxalic Acid Details
:
IUPAC Name
oxalic acid
:Chemical Class
:CAS Registry Number
144-62-7
:Description
:Fragrance Type
Physical and Chemical properties
| PUBCHEM ID | 971 |
| Molecular Weight (g/mol) | 90.0349 |
| Molecular Formula | C2H2O4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| IUPAC Name | oxalic acid |
| Canonical SMILES | O=C(O)C(=O)O |
| PUBCHEM IUPAC INCHIKEY | MUBZPKHOEPUJKR-UHFFFAOYSA-N |
| Solubility Level | 5 |
| Vapour Pressure | -3.566 |
Absorption and Metabolism information
| XLOGP3 AA | -0.3 |
| CACTVS TPSA | 74.6 |
| BBB Level | 3 |
| Absorption Level | 0 |
| EXT PPB#Prediction | 0 |
| AlogP98 | -0.429 |
| EXT CYP2D6#Prediction | 0 |
Toxicological Information
| Mouse Female FDA | Multi-Carcinogen |
| Mouse Male FDA | Multi-Carcinogen |
| Rat Female FDA | Multi-Carcinogen |
| Rat Male FDA | Multi-Carcinogen |
| Ames Prediction | Non-Mutagen |
| Developmental / Reproductive Toxicity | Toxic |
| Rat Oral LD50 | 1.33161 g/kg_body_weight |
| Ocular Irritancy | Severe |
| Hepatotoxic#Prediction | 1 |
| Effected Human Genes |
Ecological Information
| Aerobic Biodegradability Prediction | Degradable |
Hazard(s) Identification
| Physical hazards | not classified |
| Health hazards | None |
| Environmental hazards | not classified |
Compound Biological Activity
| Serial No. | Cas No | Gene Symbol | Organism | Interaction | Interaction Actions | PubMed Id |
|---|---|---|---|---|---|---|
| 1 | 144-62-7 | CASP3 | Canis lupus familiaris | Calcium Oxalate results in increased activity of CASP3 protein | increases^activity | 25446497 |
| 2 | 144-62-7 | CASP3 | Canis lupus familiaris | Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP3 protein] | decreases^reaction|increases^activity | 25446497 |
| 3 | 144-62-7 | CASP9 | Canis lupus familiaris | Calcium Oxalate results in increased activity of CASP9 protein | increases^activity | 25446497 |
| 4 | 144-62-7 | CASP9 | Canis lupus familiaris | Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP9 protein] | decreases^reaction|increases^activity | 25446497 |
| 5 | 144-62-7 | AHR | Rattus norvegicus | Oxalic Acid results in decreased activity of AHR protein | decreases^activity | 2160969 |
| 6 | 144-62-7 | AHR | Rattus norvegicus | Zinc inhibits the reaction [Oxalic Acid results in decreased activity of AHR protein] | decreases^activity|decreases^reaction | 2160969 |
| 7 | 144-62-7 | CAT | Homo sapiens | Oxalic Acid results in decreased activity of CAT protein | decreases^activity | 24145091 |
| 8 | 144-62-7 | CCL2 | Homo sapiens | Oxalic Acid results in increased expression of CCL2 mRNA | increases^expression | 24145091 |
| 9 | 144-62-7 | CCL2 | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CCL2 mRNA] | decreases^reaction|increases^expression | 24145091 |
| 10 | 144-62-7 | CYBA | Homo sapiens | Oxalic Acid results in increased expression of CYBA mRNA | increases^expression | 24145091 |
| 11 | 144-62-7 | CYBA | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CYBA mRNA] | decreases^reaction|increases^expression | 24145091 |
| 12 | 144-62-7 | HAVCR1 | Homo sapiens | Oxalic Acid results in increased expression of HAVCR1 mRNA | increases^expression | 22984472 |
| 13 | 144-62-7 | HAVCR1 | Homo sapiens | Oxalic Acid results in increased expression of HAVCR1 protein | increases^expression | 22984472 |
| 14 | 144-62-7 | ME1 | Columbidae | [malic acid co-treated with manganese chloride co-treated with NADP] inhibits the reaction [Oxalic Acid binds to ME1 protein] | affects^binding|affects^cotreatment|decreases^reaction | 7356971 |
| 15 | 144-62-7 | ME1 | Columbidae | NADP promotes the reaction [Oxalic Acid binds to ME1 protein] | affects^binding|increases^reaction | 7356971 |
| 16 | 144-62-7 | ME1 | Columbidae | Oxalic Acid binds to ME1 protein | affects^binding | 7356971 |
| 17 | 144-62-7 | NCF1 | Homo sapiens | Oxalic Acid results in increased expression of NCF1 mRNA | increases^expression | 24145091 |
| 18 | 144-62-7 | NCF1 | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of NCF1 mRNA] | decreases^reaction|increases^expression | 24145091 |
| 19 | 144-62-7 | SPP1 | Homo sapiens | Oxalic Acid results in increased expression of SPP1 mRNA | increases^expression | 24145091 |
| 20 | 144-62-7 | SPP1 | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of SPP1 mRNA] | decreases^reaction|increases^expression | 24145091 |
| 21 | 144-62-7 | TGFB1 | Homo sapiens | Oxalic Acid results in increased expression of TGFB1 protein | increases^expression | 24145091 |
| 22 | 144-62-7 | TGFB1 | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFB1 protein] | decreases^reaction|increases^expression | 24145091 |
| 23 | 144-62-7 | TGFBR1 | Homo sapiens | Oxalic Acid results in increased expression of TGFBR1 protein | increases^expression | 24145091 |
| 24 | 144-62-7 | TGFBR1 | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFBR1 protein] | decreases^reaction|increases^expression | 24145091 |
| 25 | 144-62-7 | TGFBR2 | Homo sapiens | resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFBR2 protein] | decreases^reaction|increases^expression | 24145091 |
| Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
|---|---|---|---|---|---|
| 1 | 144-62-7 | Oxalic Acid |
Compound Image
2D Structure
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