Hydrochlorothiazide Details

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Physical and Chemical properties

PUBCHEM ID	3639
CAS Registry Number	0.0
Aroma Threshold	0.0
Molecular Weight (g/mol)	297.739
Molecular Formula	C7H8ClN3O4S2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	1
IUPAC Name	6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
Canonical SMILES	NS(=O)(=O)c1cc2c(cc1Cl)NCNS2(=O)=O
PUBCHEM IUPAC INCHIKEY	JZUFKLXOESDKRF-UHFFFAOYSA-N
Solubility Level	3
Vapour Pressure	-10.144

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA	135
BBB Level	4
Absorption Level	0
EXT PPB#Prediction	0
AlogP98	-0.28
EXT CYP2D6#Prediction	0

Toxicological Information

Mouse Female FDA	Non-Carcinogen
Mouse Male FDA	Single-Carcinogen
Rat Female FDA	Non-Carcinogen
Rat Male FDA	Non-Carcinogen
Ames Prediction	Non-Mutagen
Developmental / Reproductive Toxicity	Non-Toxic
Rat Oral LD50	4.4215 g/kg_body_weight
Ocular Irritancy	Mild
Hepatotoxic#Prediction	0
Effected Human Genes

Ecological Information

Aerobic Biodegradability Prediction

Non-Degradable

Hazard(s) Identification

Physical hazards	not classified
Health hazards	None
Environmental hazards	not classified

About Table Headings

Compound Biological Activity

Serial No.	Activity Name	Details	References (PubMed)	Other details EPA (U.S)	Clinical Trials (U.S. NIH)
1				58-93-5	Hydrochlorothiazide

Plant Variety and Essential oils

Serial No.	Plant Name	Variety Name	Essential Oil	Compound Percentage
1	Mulethi	Mishri	Glucyrrhiza glabra mulethi