CSIR CIMAP AROMA | Compound Details

Acetovanillone Details

: IUPAC Name

1-(4-hydroxy-3-methoxyphenyl)ethanone

:Chemical Class

Ketone

:CAS Registry Number

498-02-2

:Description

:Fragrance Type

vanilla

Physical and Chemical properties

PUBCHEM ID	2214
Molecular Weight (g/mol)	166.174
Molecular Formula	C9H10O3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
IUPAC Name	1-(4-hydroxy-3-methoxyphenyl)ethanone
Canonical SMILES	COc1cc(C(C)=O)ccc1O
PUBCHEM IUPAC INCHIKEY	DFYRUELUNQRZTB-UHFFFAOYSA-N
Solubility Level	4
Vapour Pressure

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA	46.5
BBB Level	2
Absorption Level	0
EXT PPB#Prediction	0
AlogP98	1.311
EXT CYP2D6#Prediction	0

Toxicological Information

Mouse Female FDA	Non-Carcinogen
Mouse Male FDA	Multi-Carcinogen
Rat Female FDA	Non-Carcinogen
Rat Male FDA	Non-Carcinogen
Ames Prediction	Non-Mutagen
Developmental / Reproductive Toxicity	Toxic
Rat Oral LD50	1.20625 g/kg_body_weight
Ocular Irritancy	Mild
Hepatotoxic#Prediction	0
Effected Human Genes

Ecological Information

Aerobic Biodegradability Prediction	Degradable

Hazard(s) Identification

Physical hazards	not classified
Health hazards	Mild
Environmental hazards	not classified

About Table Headings

Compound Biological Activity

Serial No.	Cas No	Gene Symbol	Organism	Interaction	Interaction Actions	PubMed Id
1	498-02-2	AGT	Homo sapiens	[acetovanillone co-treated with AGT protein] results in increased expression of and affects the localization of NFE2L2 protein	affects^cotreatment\|affects^localization\|increases^expression	27983965
2	498-02-2	AGT	Mus musculus	acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA]	decreases^reaction\|increases^expression	17391658
3	498-02-2	AGT	Rattus norvegicus	acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 mRNA]	decreases^reaction\|increases^expression	16531806
4	498-02-2	AGT	Rattus norvegicus	acetovanillone inhibits the reaction [AGT protein results in increased expression of COL1A2 protein]	decreases^reaction\|increases^expression	16531806
5	498-02-2	AGT	Rattus norvegicus	acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 mRNA]	decreases^reaction\|increases^expression	16531806
6	498-02-2	AGT	Rattus norvegicus	acetovanillone inhibits the reaction [AGT protein results in increased expression of COL3A1 protein]	decreases^reaction\|increases^expression	16531806
7	498-02-2	AGT	Rattus norvegicus	acetovanillone inhibits the reaction [AGT protein results in increased expression of PTGS2 protein]	decreases^reaction\|increases^expression	17244722
8	498-02-2	AGT	Rattus norvegicus	acetovanillone results in decreased activity of AGT protein	decreases^activity	17224469
9	498-02-2	AIF1	Mus musculus	acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein]	affects^cotreatment\|decreases^reaction\|increases^expression	28202386
10	498-02-2	ALPL	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA]	decreases^reaction\|increases^expression	24080574
11	498-02-2	BAX	Rattus norvegicus	acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]	affects^cotreatment\|decreases^reaction\|increases^expression	22431579
12	498-02-2	BCL2	Rattus norvegicus	acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]	affects^cotreatment\|decreases^expression\|decreases^reaction	22431579
13	498-02-2	BGLAP	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of BGLAP mRNA]	decreases^reaction\|increases^expression	24080574
14	498-02-2	CASP1	Homo sapiens	acetovanillone inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]	decreases^reaction\|increases^expression	26079697
15	498-02-2	CASP3	Homo sapiens	[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione results in increased activity of CASP3 protein]	affects^cotreatment\|decreases^reaction\|increases^activity	20153346
16	498-02-2	CASP3	Rattus norvegicus	acetovanillone inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]	decreases^reaction\|increases^activity	24291008
17	498-02-2	CASP3	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased cleavage of and results in increased activity of CASP3 protein]	decreases^reaction\|increases^activity\|increases^cleavage	22497828
18	498-02-2	CASP3	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of CASP3 protein]	decreases^reaction\|increases^expression	26522475
19	498-02-2	CAT	Rattus norvegicus	acetovanillone inhibits the reaction [Cisplatin results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	24291008
20	498-02-2	CAT	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of CAT mRNA]	decreases^reaction\|increases^expression	21983654
21	498-02-2	CCL11	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]	decreases^reaction\|increases^expression	22414048
22	498-02-2	CCL2	Homo sapiens	acetovanillone inhibits the reaction [Homocysteine results in increased expression of CCL2 mRNA]	decreases^reaction\|increases^expression	16845898
23	498-02-2	CCL2	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]	decreases^reaction\|increases^expression	22414048
24	498-02-2	CCL2	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL2 protein]	decreases^reaction\|increases^expression	22414048
25	498-02-2	CCL2	Sus scrofa	acetovanillone inhibits the reaction [titanium dioxide results in increased expression of CCL2 mRNA]	decreases^reaction\|increases^expression	23380242
26	498-02-2	CCL2	Sus scrofa	acetovanillone results in decreased expression of CCL2 mRNA	decreases^expression	23380242
27	498-02-2	CCL5	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 protein]	decreases^reaction\|increases^expression	22414048
28	498-02-2	CCL5	Mus musculus	acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]	decreases^reaction\|increases^expression	10495789
29	498-02-2	CCL7	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CCL7 mRNA]	decreases^reaction\|increases^expression	22414048
30	498-02-2	CD36	Homo sapiens	acetovanillone inhibits the reaction [[Oxygen deficiency results in increased abundance of Reactive Oxygen Species] which results in increased expression of CD36 mRNA]	decreases^reaction\|increases^abundance\|increases^expression	19640849
31	498-02-2	CDH3	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in decreased expression of CDH3 protein]	decreases^expression\|decreases^reaction	21647593
32	498-02-2	CSF2	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CSF2 mRNA]	decreases^reaction\|increases^expression	22414048
33	498-02-2	CTF1	Mus musculus	acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of CTF1 protein]	decreases^reaction\|increases^expression	16507596
34	498-02-2	CTF1	Mus musculus	acetovanillone inhibits the reaction [Vitamin K 3 results in increased expression of CTF1 protein]	decreases^reaction\|increases^expression	16507596
35	498-02-2	CXCL1	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]	decreases^reaction\|increases^expression	22414048
36	498-02-2	CXCL1	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL1 protein]	decreases^reaction\|increases^expression	22414048
37	498-02-2	CXCL10	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA]	decreases^reaction\|increases^expression	22414048
38	498-02-2	CXCL10	Homo sapiens	acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of CXCL10 mRNA]	decreases^reaction\|increases^expression	18322232
39	498-02-2	CXCL8	Homo sapiens	acetovanillone inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]	decreases^reaction\|increases^expression	27393034
40	498-02-2	CXCL8	Homo sapiens	acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]	decreases^reaction\|increases^expression	20920494
41	498-02-2	CXCL8	Homo sapiens	acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 protein]	decreases^reaction\|increases^expression	20920494
42	498-02-2	CXCL8	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]	decreases^reaction\|increases^expression	22414048
43	498-02-2	CXCL8	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]	decreases^reaction\|increases^expression	22414048
44	498-02-2	CYBA	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]	decreases^reaction\|increases^expression	23270704
45	498-02-2	CYBA	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein]	decreases^reaction\|increases^expression	23270704
46	498-02-2	CYBB	Homo sapiens	acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of CYBB protein]	decreases^reaction\|increases^activity\|increases^expression	19878672
47	498-02-2	CYBB	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB mRNA]	decreases^reaction\|increases^expression	23270704
48	498-02-2	CYBB	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBB protein]	decreases^reaction\|increases^expression	23270704
49	498-02-2	CYBB	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of CYBB mRNA]	decreases^reaction\|increases^expression	24080574
50	498-02-2	DES	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES mRNA]	decreases^reaction\|increases^expression	20036696
51	498-02-2	DES	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in increased expression of DES protein]	decreases^reaction\|increases^expression	20036696
52	498-02-2	DMD	Mus musculus	acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of RELA protein modified form]	decreases^reaction\|increases^expression	26930420
53	498-02-2	DMD	Mus musculus	acetovanillone inhibits the reaction [DMD gene mutant form results in increased expression of SIRT1 mRNA]	decreases^reaction\|increases^expression	26930420
54	498-02-2	EDN1	Rattus norvegicus	acetovanillone inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine]	decreases^reaction\|decreases^response to substance	20977430
55	498-02-2	EDNRA	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRA mRNA]	decreases^reaction\|increases^expression	23270704
56	498-02-2	EDNRA	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EDNRA protein]	decreases^reaction\|increases^expression	23270704
57	498-02-2	EIF2AK3	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA]	decreases^reaction\|increases^expression	23270704
58	498-02-2	EIF2AK3	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 protein]	decreases^reaction\|increases^expression	23270704
59	498-02-2	EP300	Homo sapiens	acetovanillone inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]	affects^binding\|decreases^reaction\|increases^reaction	19281832
60	498-02-2	FN1	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]	decreases^reaction\|increases^expression\|increases^secretion	16632126
61	498-02-2	FN1	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]	decreases^reaction\|increases^expression	16632126
62	498-02-2	FN1	Rattus norvegicus	acetovanillone inhibits the reaction [Glucose results in increased expression of FN1 protein]	decreases^reaction\|increases^expression	22245600
63	498-02-2	FSHB	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of FSHB protein]	decreases^reaction\|increases^expression	23270704
64	498-02-2	GAD1	Mus musculus	acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein]	decreases^expression\|decreases^reaction	18063801
65	498-02-2	GJA1	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of GJA1 mRNA]	decreases^expression\|decreases^reaction	23270704
66	498-02-2	GJA1	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of GJA1 protein]	decreases^expression\|decreases^reaction	23270704
67	498-02-2	GNA11	Rattus norvegicus	acetovanillone inhibits the reaction [Glucose results in increased expression of GNA11 protein]	decreases^reaction\|increases^expression	20691780
68	498-02-2	GNA11	Rattus norvegicus	acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]	decreases^reaction\|increases^expression	20691780
69	498-02-2	GNAQ	Rattus norvegicus	acetovanillone inhibits the reaction [Glucose results in increased expression of GNAQ protein]	decreases^reaction\|increases^expression	20691780
70	498-02-2	GNAQ	Rattus norvegicus	acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]	decreases^reaction\|increases^expression	20691780
71	498-02-2	GPX1	Rattus norvegicus	acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]	affects^cotreatment\|decreases^expression\|decreases^reaction	22431579
72	498-02-2	GPX3	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of GPX3 mRNA]	decreases^reaction\|increases^expression	21983654
73	498-02-2	GUCY1A3	Rattus norvegicus	acetovanillone results in increased expression of GUCY1A3 protein	increases^expression	25217652
74	498-02-2	GUCY1B3	Rattus norvegicus	acetovanillone results in increased expression of GUCY1B3 protein	increases^expression	25217652
75	498-02-2	GYPA	Homo sapiens	acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]	decreases^expression\|decreases^reaction	20523355
76	498-02-2	HIF1A	Homo sapiens	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]	decreases^reaction\|increases^expression	23144690
77	498-02-2	HIF1A	Rattus norvegicus	acetovanillone results in increased expression of HIF1A protein	increases^expression	12595275
78	498-02-2	HMOX1	Homo sapiens	acetovanillone inhibits the reaction [Cadmium Chloride results in increased activity of HMOX1 protein]	decreases^reaction\|increases^activity	20934533
79	498-02-2	HMOX1	Homo sapiens	acetovanillone inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]	decreases^reaction\|increases^expression	20934533
80	498-02-2	HMOX1	Homo sapiens	acetovanillone inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	20934533
81	498-02-2	HMOX1	Homo sapiens	acetovanillone inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	26945724
82	498-02-2	HMOX1	Homo sapiens	acetovanillone inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	19414066
83	498-02-2	HMOX1	Mus musculus	acetovanillone results in decreased expression of HMOX1 mRNA	decreases^expression	21690482
84	498-02-2	HMOX1	Rattus norvegicus	acetovanillone inhibits the reaction [Cisplatin results in increased expression of HMOX1 mRNA]	decreases^reaction\|increases^expression	24291008
85	498-02-2	HTRA2	Homo sapiens	[tempol co-treated with UCF 101 co-treated with acetovanillone] inhibits the reaction [S-Nitrosoglutathione affects the localization of HTRA2 protein]	affects^cotreatment\|affects^localization\|decreases^reaction	20153346
86	498-02-2	ICAM1	Homo sapiens	acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of ICAM1 protein]	decreases^reaction\|increases^expression	19632255
87	498-02-2	ICAM1	Homo sapiens	acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]	decreases^reaction\|increases^expression	20920494
88	498-02-2	ICAM1	Homo sapiens	acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein]	decreases^reaction\|increases^expression	20920494
89	498-02-2	ICAM1	Homo sapiens	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ICAM1 protein]	decreases^reaction\|increases^expression	26901245
90	498-02-2	ICAM1	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]	decreases^reaction\|increases^expression	22414048
91	498-02-2	ICAM1	Mus musculus	acetovanillone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]	decreases^reaction\|increases^expression	10495789
92	498-02-2	ICAM1	Mus musculus	acetovanillone results in decreased expression of ICAM1 protein	decreases^expression	19417757
93	498-02-2	IFNB1	Homo sapiens	acetovanillone inhibits the reaction [vanadium pentoxide results in increased expression of IFNB1 mRNA]	decreases^reaction\|increases^expression	18322232
94	498-02-2	IFNG	Rattus norvegicus	acetovanillone results in decreased susceptibility to [IFNG protein co-treated with Lipopolysaccharides]	affects^cotreatment\|decreases^response to substance	16307444
95	498-02-2	IL1B	Homo sapiens	acetovanillone inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]	decreases^reaction\|increases^expression	21211511
96	498-02-2	IL1B	Homo sapiens	acetovanillone inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]	decreases^reaction\|increases^expression	27393034
97	498-02-2	IL1B	Homo sapiens	acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]	decreases^reaction\|increases^expression	19281832
98	498-02-2	IL1B	Homo sapiens	acetovanillone inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]	decreases^reaction\|increases^expression	19281832
99	498-02-2	IL1B	Homo sapiens	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]	decreases^reaction\|increases^expression	26901245
100	498-02-2	IL1B	Homo sapiens	acetovanillone results in decreased susceptibility to IL1B protein	decreases^response to substance	21211511
101	498-02-2	IL1B	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of IL1B protein]	decreases^reaction\|increases^expression	26522475
102	498-02-2	IL1B	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL1B protein]	decreases^reaction\|increases^expression	21983654
103	498-02-2	IL1B		acetovanillone inhibits the reaction [IL1B protein results in increased expression of MAPK1 protein modified form]	decreases^reaction\|increases^expression	19375465
104	498-02-2	IL1B		acetovanillone inhibits the reaction [IL1B protein results in increased expression of PLA2G2A mRNA]	decreases^reaction\|increases^expression	19375465
105	498-02-2	IL6	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]	decreases^reaction\|increases^expression	22414048
106	498-02-2	IL6	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of IL6 protein]	decreases^reaction\|increases^expression	22414048
107	498-02-2	IL6	Mus musculus	acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of IL6 protein]	decreases^reaction\|increases^expression	22472292
108	498-02-2	IL6	Mus musculus	acetovanillone inhibits the reaction [di-n-butyltin results in increased expression of IL6 mRNA]	decreases^reaction\|increases^expression	24631921
109	498-02-2	IL6	Mus musculus	acetovanillone inhibits the reaction [di-n-butyltin results in increased expression of IL6 protein]	decreases^reaction\|increases^expression	24631921
110	498-02-2	IL6	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of IL6 protein]	decreases^reaction\|increases^expression	21983654
111	498-02-2	ITGA2B	Homo sapiens	acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]	decreases^reaction\|increases^expression	20523355
112	498-02-2	ITGAM	Homo sapiens	acetovanillone inhibits the reaction [Fatty Acids, Nonesterified results in increased expression of ITGAM mRNA]	decreases^reaction\|increases^expression	16357311
113	498-02-2	ITGAM	Mus musculus	acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ITGAM protein]	affects^cotreatment\|decreases^reaction\|increases^expression	28202386
114	498-02-2	ITGB3	Homo sapiens	acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]	decreases^reaction\|increases^expression	20523355
115	498-02-2	JUN	Homo sapiens	acetovanillone inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of and results in increased expression of JUN protein]	decreases^reaction\|increases^expression\|increases^phosphorylation	22288910
116	498-02-2	LEP	Mus musculus	acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF1 protein]	decreases^reaction\|increases^expression	16380530
117	498-02-2	LEP	Mus musculus	acetovanillone inhibits the reaction [LEP protein results in increased expression of NCF2 protein]	decreases^reaction\|increases^expression	16380530
118	498-02-2	LEPR	Mus musculus	acetovanillone inhibits the reaction [LEPR gene mutant form results in decreased susceptibility to Acetylcholine]	decreases^reaction\|decreases^response to substance	19478208
119	498-02-2	LHB	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of LHB protein]	decreases^reaction\|increases^expression	23270704
120	498-02-2	MAPK1	Mus musculus	acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]	decreases^reaction\|increases^activity\|increases^phosphorylation	20354174
121	498-02-2	MAPK3	Mus musculus	acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]	decreases^reaction\|increases^activity\|increases^phosphorylation	20354174
122	498-02-2	MAPK8	Mus musculus	acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein]	decreases^reaction\|increases^activity\|increases^phosphorylation	20354174
123	498-02-2	MIF	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of MIF mRNA]	decreases^reaction\|increases^expression	22414048
124	498-02-2	MMP13	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP13 protein]	decreases^reaction\|increases^expression	21211511
125	498-02-2	MMP9	Homo sapiens	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]	decreases^reaction\|increases^expression	26514923
126	498-02-2	MMP9	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 mRNA]	decreases^reaction\|increases^expression	23270704
127	498-02-2	MMP9	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MMP9 protein]	decreases^reaction\|increases^expression	23270704
128	498-02-2	MMP9	Rattus norvegicus	acetovanillone inhibits the reaction [RELA protein binds to MMP9 promoter]	affects^binding\|decreases^reaction	23774252
129	498-02-2	MMP9	Rattus norvegicus	acetovanillone inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]	decreases^reaction\|increases^expression\|increases^secretion	23774252
130	498-02-2	MMP9	Rattus norvegicus	acetovanillone inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]	decreases^reaction\|increases^expression	23774252
131	498-02-2	MPO	Mus musculus	acetovanillone results in decreased expression of MPO protein	decreases^expression	19417757
132	498-02-2	MPO	Rattus norvegicus	acetovanillone inhibits the reaction [Cisplatin results in increased activity of MPO protein]	decreases^reaction\|increases^activity	24291008
133	498-02-2	MSR1	Homo sapiens	acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]	decreases^reaction\|increases^expression	9614211
134	498-02-2	MYL9	Bos taurus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of MYL9 protein modified form]	decreases^reaction\|increases^expression	17419808
135	498-02-2	NCF1	Bos taurus	acetovanillone inhibits the reaction [Glucose results in increased expression of NCF1 protein]	decreases^reaction\|increases^expression	22284404
136	498-02-2	NCF1	Homo sapiens	acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of NCF1 protein]	decreases^reaction\|increases^activity\|increases^expression	19878672
137	498-02-2	NCF1	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 mRNA]	decreases^reaction\|increases^expression	23270704
138	498-02-2	NCF1	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 protein]	decreases^reaction\|increases^expression	23270704
139	498-02-2	NCF1	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF1 mRNA]	decreases^reaction\|increases^expression	24080574
140	498-02-2	NCF1		acetovanillone inhibits the reaction [NCF1 protein binds to NCF2 protein]	affects^binding\|decreases^reaction	22431579
141	498-02-2	NCF2	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NCF2 mRNA]	decreases^reaction\|increases^expression	24080574
142	498-02-2	NFE2L2	Rattus norvegicus	acetovanillone inhibits the reaction [Cisplatin results in increased expression of NFE2L2 mRNA]	decreases^reaction\|increases^expression	24291008
143	498-02-2	NFE2L2	Sus scrofa	acetovanillone inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein]	decreases^reaction\|increases^activity	24512358
144	498-02-2	NFKBIA	Homo sapiens	acetovanillone inhibits the reaction [Homocysteine results in increased phosphorylation of and results in increased activity of NFKBIA protein]	decreases^reaction\|increases^activity\|increases^phosphorylation	16845898
145	498-02-2	NFKBIA	Mus musculus	acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of and results in decreased expression of NFKBIA protein]	affects^cotreatment\|decreases^expression\|decreases^reaction\|increases^phosphorylation	28202386
146	498-02-2	NLRP3	Homo sapiens	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of and results in decreased ubiquitination of NLRP3 protein]	decreases^reaction\|decreases^ubiquitination\|increases^expression	26901245
147	498-02-2	NOS2	Mus musculus	acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	28202386
148	498-02-2	NOS2	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of NOS2 protein]	decreases^reaction\|increases^expression	26522475
149	498-02-2	NOS2	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of NOS2 mRNA]	decreases^reaction\|increases^expression	21983654
150	498-02-2	NOS3	Bos taurus	acetovanillone inhibits the reaction [Nitroglycerin results in increased expression of NOS3 mRNA]	decreases^reaction\|increases^expression	17449545
151	498-02-2	NOS3	Bos taurus	acetovanillone inhibits the reaction [Nitroglycerin results in increased expression of NOS3 protein]	decreases^reaction\|increases^expression	17449545
152	498-02-2	NOS3	Homo sapiens	acetovanillone inhibits the reaction [Glucose results in decreased expression of NOS3 protein]	decreases^expression\|decreases^reaction	19878672
153	498-02-2	NOS3	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of NOS3 mRNA]	decreases^reaction\|increases^expression	21983654
154	498-02-2	NOS3	Rattus norvegicus	acetovanillone results in increased expression of NOS3 protein	increases^expression	23703608
155	498-02-2	NOS3	Rattus norvegicus	[Cadmium co-treated with acetovanillone] results in increased expression of NOS3 protein	affects^cotreatment\|increases^expression	23703608
156	498-02-2	NOX1	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of NOX1 protein]	decreases^reaction\|increases^expression	26522475
157	498-02-2	NOX4	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of NOX4 protein]	decreases^reaction\|increases^expression	26522475
158	498-02-2	NOXA1	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXA1 mRNA]	decreases^reaction\|increases^expression	24080574
159	498-02-2	NOXO1	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of NOXO1 mRNA]	decreases^reaction\|increases^expression	24080574
160	498-02-2	NPHS1	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS1 mRNA]	decreases^expression\|decreases^reaction	20036696
161	498-02-2	NPHS1	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS1 protein]	decreases^expression\|decreases^reaction	20036696
162	498-02-2	NPHS2	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 mRNA]	decreases^expression\|decreases^reaction	20036696
163	498-02-2	NPHS2	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in decreased expression of NPHS2 protein]	decreases^expression\|decreases^reaction	20036696
164	498-02-2	OLR1	Homo sapiens	acetovanillone inhibits the reaction [Glucose results in increased expression of OLR1 mRNA]	decreases^reaction\|increases^expression	19878672
165	498-02-2	PARP1	Mus musculus	acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein]	decreases^reaction\|increases^activity	18509044
166	498-02-2	PCK1	Oryctolagus cuniculus	[acetovanillone co-treated with Alloxan] results in decreased activity of PCK1 protein	affects^cotreatment\|decreases^activity	20934416
167	498-02-2	PCK2	Oryctolagus cuniculus	acetovanillone inhibits the reaction [Alloxan results in increased activity of PCK2 protein]	decreases^reaction\|increases^activity	20934416
168	498-02-2	PCNA	Rattus norvegicus	acetovanillone inhibits the reaction [Ozone results in increased expression of PCNA protein]	decreases^reaction\|increases^expression	9517619
169	498-02-2	PDE5A	Oryctolagus cuniculus	acetovanillone inhibits the reaction [[cupric chloride co-treated with Homocysteine] results in increased expression of PDE5A protein]	affects^cotreatment\|decreases^reaction\|increases^expression	18097500
170	498-02-2	PLCB1	Rattus norvegicus	acetovanillone inhibits the reaction [Glucose results in increased expression of PLCB1 protein]	decreases^reaction\|increases^expression	20691780
171	498-02-2	PLCB1	Rattus norvegicus	acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]	decreases^reaction\|increases^expression	20691780
172	498-02-2	PLCB2	Rattus norvegicus	acetovanillone inhibits the reaction [Glucose results in increased expression of PLCB2 protein]	decreases^reaction\|increases^expression	20691780
173	498-02-2	PLCB2	Rattus norvegicus	acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]	decreases^reaction\|increases^expression	20691780
174	498-02-2	PRKG1	Rattus norvegicus	acetovanillone inhibits the reaction [Glucose results in decreased expression of PRKG1 protein]	decreases^expression\|decreases^reaction	17320767
175	498-02-2	PTGS1	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of PTGS1 mRNA]	decreases^reaction\|increases^expression	21983654
176	498-02-2	PTGS1	Rattus norvegicus	acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein]	decreases^reaction\|increases^expression	18414395
177	498-02-2	PTGS2	Homo sapiens	acetovanillone inhibits the reaction [2-aminodiphenyl results in increased expression of PTGS2 protein]	decreases^reaction\|increases^expression	22288910
178	498-02-2	PTGS2	Homo sapiens	acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]	decreases^reaction\|increases^expression	24967690
179	498-02-2	PTGS2	Mus musculus	acetovanillone inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]	decreases^reaction\|increases^expression	24337631
180	498-02-2	PTGS2	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]	decreases^reaction\|increases^expression	26522475
181	498-02-2	PTGS2	Rattus norvegicus	acetovanillone inhibits the reaction [Mercuric Chloride results in increased expression of PTGS2 mRNA]	decreases^reaction\|increases^expression	23415682
182	498-02-2	PTGS2	Rattus norvegicus	acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]	decreases^reaction\|increases^expression	18414395
183	498-02-2	PTGS2	Rattus norvegicus	acetovanillone results in decreased expression of PTGS2 mRNA	decreases^expression	21983654
184	498-02-2	PVALB	Mus musculus	acetovanillone inhibits the reaction [Ketamine results in decreased expression of PVALB protein]	decreases^expression\|decreases^reaction	18063801
185	498-02-2	PYCARD	Homo sapiens	acetovanillone inhibits the reaction [Ethanol results in increased expression of PYCARD protein]	decreases^reaction\|increases^expression	26079697
186	498-02-2	RAC1		acetovanillone results in decreased activity of RAC1 protein	decreases^activity	19632255
187	498-02-2	RELA	Mus musculus	acetovanillone inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein]	decreases^reaction\|increases^activity\|increases^phosphorylation	20354174
188	498-02-2	RELA	Mus musculus	acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of RELA protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	28202386
189	498-02-2	RUNX2	Rattus norvegicus	acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of RUNX2 mRNA]	decreases^reaction\|increases^expression	24080574
190	498-02-2	S100A4	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in increased expression of S100A4 protein]	decreases^reaction\|increases^expression	21647593
191	498-02-2	SELE	Homo sapiens	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]	decreases^reaction\|increases^expression	26901245
192	498-02-2	SERPINE1	Homo sapiens	acetovanillone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]	decreases^reaction\|increases^expression	22414048
193	498-02-2	SHC1	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of SHC1 mRNA]	decreases^reaction\|increases^expression	23270704
194	498-02-2	SHC1	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of SHC1 protein]	decreases^reaction\|increases^expression	23270704
195	498-02-2	SOD1	Rattus norvegicus	acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]	affects^cotreatment\|decreases^expression\|decreases^reaction	22431579
196	498-02-2	SOD1	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of SOD1 mRNA]	decreases^reaction\|increases^expression	21983654
197	498-02-2	SOD2	Rattus norvegicus	acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]	affects^cotreatment\|decreases^expression\|decreases^reaction	22431579
198	498-02-2	SOD2	Rattus norvegicus	acetovanillone inhibits the reaction [Formaldehyde results in increased expression of SOD2 mRNA]	decreases^reaction\|increases^expression	21983654
199	498-02-2	STAR	Rattus norvegicus	acetovanillone inhibits the reaction [Hydrogen Peroxide deficiency results in decreased expression of STAR protein]	decreases^expression\|decreases^reaction	23270704
200	498-02-2	STAR	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of STAR mRNA]	decreases^expression\|decreases^reaction	23270704
201	498-02-2	STAR	Rattus norvegicus	acetovanillone inhibits the reaction [Oxygen deficiency results in decreased expression of STAR protein]	decreases^expression\|decreases^reaction	23270704
202	498-02-2	TH	Rattus norvegicus	acetovanillone results in decreased expression of TH mRNA	decreases^expression	25217652
203	498-02-2	TJP1	Homo sapiens	acetovanillone inhibits the reaction [2,2',4,6,6'-pentachlorobiphenyl results in decreased expression of TJP1 protein]	decreases^expression\|decreases^reaction	20299304
204	498-02-2	TJP1	Homo sapiens	acetovanillone inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in decreased expression of TJP1 protein]	decreases^expression\|decreases^reaction	20299304
205	498-02-2	TJP1	Homo sapiens	acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of TJP1 protein]	decreases^expression\|decreases^reaction	20299304
206	498-02-2	TJP1	Homo sapiens	acetovanillone inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]	decreases^expression\|decreases^reaction	20299304
207	498-02-2	TJP1	Mus musculus	acetovanillone inhibits the reaction [Homocysteine results in decreased expression of TJP1 protein]	decreases^expression\|decreases^reaction	21647593
208	498-02-2	TNF	Homo sapiens	acetovanillone results in decreased susceptibility to TNF protein	decreases^response to substance	21211511
209	498-02-2	TNF	Mus musculus	acetovanillone inhibits the reaction [cobaltous chloride results in increased expression of TNF protein]	decreases^reaction\|increases^expression	22472292
210	498-02-2	TNF	Mus musculus	acetovanillone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]	decreases^reaction\|increases^expression	15795323
211	498-02-2	TNF	Mus musculus	acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	28202386
212	498-02-2	TNF	Rattus norvegicus	acetovanillone inhibits the reaction [Cisplatin results in increased expression of TNF protein]	decreases^reaction\|increases^expression	24291008
213	498-02-2	TNF	Rattus norvegicus	acetovanillone inhibits the reaction [Ethanol results in increased expression of TNF protein]	decreases^reaction\|increases^expression	26522475
214	498-02-2	TP53	Rattus norvegicus	acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]	affects^cotreatment\|decreases^reaction\|increases^expression	22431579
215	498-02-2	VCAM1	Homo sapiens	acetovanillone inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of VCAM1 protein]	decreases^reaction\|increases^expression	19632255
216	498-02-2	VCAM1	Homo sapiens	acetovanillone inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein]	decreases^reaction\|increases^expression	26901245
217	498-02-2	VCAM1	Sus scrofa	acetovanillone inhibits the reaction [titanium dioxide results in increased expression of VCAM1 mRNA]	decreases^reaction\|increases^expression	23380242
218	498-02-2	XDH	Rattus norvegicus	acetovanillone inhibits the reaction [Cocaine results in increased activity of XDH protein]	decreases^reaction\|increases^activity	17217956

Serial No.	Activity Name	Details	References (PubMed)	Other details EPA (U.S)	Clinical Trials (U.S. NIH)
1				498-02-2	Acetovanillone

Print Back

Compound Image

2D Structure

Download

Download Sdf File Download PDB File Download MOL File

View Similar Structures (External DB)

AromaDb: A Database of Plant's Aroma Molecules

AROMA: A Database of Plant's Aroma Molecules