Acetylformaldehyde Details
:
IUPAC Name
Pyruvaldehyde
:Chemical Class
:CAS Registry Number
78-98-8
:Description
:Fragrance Type
NA
Physical and Chemical properties
| PUBCHEM ID | 880 |
| Molecular Weight (g/mol) | 72.065 |
| Molecular Formula | C3H4O2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 1 |
| IUPAC Name | Pyruvaldehyde |
| Canonical SMILES | CC(=O)C=O |
| PUBCHEM IUPAC INCHIKEY | AIJULSRZWUXGPQ-UHFFFAOYSA-N |
| Solubility Level | 5 |
| Vapour Pressure | 1.628 |
Absorption and Metabolism information
| XLOGP3 AA | NA |
| CACTVS TPSA | 17.07 |
| BBB Level | 3 |
| Absorption Level | 1 |
| EXT PPB#Prediction | 0 |
| AlogP98 | -0.307 |
| EXT CYP2D6#Prediction | 0 |
Toxicological Information
| Mouse Female FDA | Single-Carcinogen |
| Mouse Male FDA | Multi-Carcinogen |
| Rat Female FDA | Multi-Carcinogen |
| Rat Male FDA | Multi-Carcinogen |
| Ames Prediction | Non-Mutagen |
| Developmental / Reproductive Toxicity | Toxic |
| Rat Oral LD50 | 0.858881 |
| Ocular Irritancy | Mild |
| Hepatotoxic#Prediction | 1 |
| Effected Human Genes | NA |
Ecological Information
| Aerobic Biodegradability Prediction | Degradable |
Hazard(s) Identification
| Physical hazards | not classified |
| Health hazards | Mild |
| Environmental hazards | not classified |
Compound Biological Activity
| Serial No. | Cas No | Gene Symbol | Organism | Interaction | Interaction Actions | PubMed Id |
|---|---|---|---|---|---|---|
| 1 | 78-98-8 | ACTA2 | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of ACTA2 protein] | decreases^reaction|increases^expression | 22101032 |
| 2 | 78-98-8 | ACTA2 | Mus musculus | Pyruvaldehyde results in increased expression of ACTA2 protein | increases^expression | 22101032 |
| 3 | 78-98-8 | ADGRE1 | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of ADGRE1 protein] | decreases^reaction|increases^expression | 22101032 |
| 4 | 78-98-8 | ADGRE1 | Mus musculus | Pyruvaldehyde results in increased expression of ADGRE1 protein | increases^expression | 22101032 |
| 5 | 78-98-8 | AGER | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of AGER protein] | decreases^reaction|increases^expression | 22101032 |
| 6 | 78-98-8 | AGER | Mus musculus | Pyruvaldehyde results in increased expression of AGER protein | increases^expression | 22101032 |
| 7 | 78-98-8 | AGT | Rattus norvegicus | Pyruvaldehyde affects the expression of AGT protein | affects^expression | 24402234 |
| 8 | 78-98-8 | AKR1B8 | Rattus norvegicus | [AKR1B8 protein co-treated with NADP] affects the reduction of Pyruvaldehyde | affects^cotreatment|affects^reduction | 18845131 |
| 9 | 78-98-8 | AKR1C3 | Homo sapiens | Pyruvaldehyde results in increased expression of AKR1C3 mRNA | increases^expression | 25451587 |
| 10 | 78-98-8 | AKR7A2 | Homo sapiens | AKR7A2 protein results in decreased susceptibility to Pyruvaldehyde | decreases^response to substance | 22001351|25451587 |
| 11 | 78-98-8 | AKR7A2 | Homo sapiens | Pyruvaldehyde results in increased expression of AKR7A2 mRNA | increases^expression | 25451587 |
| 12 | 78-98-8 | AKR7A2 | Homo sapiens | Pyruvaldehyde results in increased expression of AKR7A2 protein | increases^expression | 25451587 |
| 13 | 78-98-8 | AKR7A5 | Mus musculus | AKR7A5 protein results in decreased susceptibility to Pyruvaldehyde | decreases^response to substance | 24590062 |
| 14 | 78-98-8 | ALB | Homo sapiens | [ALB protein binds to Myristic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein] | affects^binding|increases^oxidation|increases^reaction | 25451573 |
| 15 | 78-98-8 | ALB | Homo sapiens | [ALB protein binds to Oleic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein] | affects^binding|increases^oxidation|increases^reaction | 25451573 |
| 16 | 78-98-8 | ALB | Homo sapiens | [ALB protein binds to Palmitic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein] | affects^binding|increases^oxidation|increases^reaction | 25451573 |
| 17 | 78-98-8 | ALB | Homo sapiens | [ALB protein binds to stearic acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein] | affects^binding|increases^oxidation|increases^reaction | 25451573 |
| 18 | 78-98-8 | ALB | Homo sapiens | Pyruvaldehyde binds to ALB protein | affects^binding | 20934417 |
| 19 | 78-98-8 | ALB | Homo sapiens | [Pyruvaldehyde binds to ALB protein] which results in decreased metabolism of Prostaglandins | affects^binding|decreases^metabolic processing | 20934417 |
| 20 | 78-98-8 | ALB | Homo sapiens | Pyruvaldehyde inhibits the reaction [Warfarin binds to ALB protein] | affects^binding|decreases^reaction | 20934417 |
| 21 | 78-98-8 | ALDH2 | Rattus norvegicus | [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde | decreases^activity|increases^response to substance | 21334317 |
| 22 | 78-98-8 | ALDH2 | Rattus norvegicus | [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde | decreases^activity|increases^response to substance | 21334317 |
| 23 | 78-98-8 | BAX | Homo sapiens | Pyruvaldehyde results in increased expression of BAX protein | increases^expression | 26577515 |
| 24 | 78-98-8 | BAX | Homo sapiens | salvin inhibits the reaction [Pyruvaldehyde results in increased expression of BAX protein] | decreases^reaction|increases^expression | 26577515 |
| 25 | 78-98-8 | BCL2 | Homo sapiens | Pyruvaldehyde results in decreased expression of BCL2 protein | decreases^expression | 26577515 |
| 26 | 78-98-8 | BCL2 | Homo sapiens | salvin inhibits the reaction [Pyruvaldehyde results in decreased expression of BCL2 protein] | decreases^expression|decreases^reaction | 26577515 |
| 27 | 78-98-8 | BDNF | Homo sapiens | Pyruvaldehyde results in increased expression of BDNF protein | increases^expression | 25933243 |
| 28 | 78-98-8 | BDNF | Homo sapiens | sulforafan promotes the reaction [Pyruvaldehyde results in increased expression of BDNF protein] | increases^expression|increases^reaction | 25933243 |
| 29 | 78-98-8 | CASP3 | Homo sapiens | Pyruvaldehyde results in increased activity of CASP3 protein | increases^activity | 25933243 |
| 30 | 78-98-8 | CASP3 | Homo sapiens | Pyruvaldehyde results in increased expression of CASP3 protein | increases^expression | 26577515 |
| 31 | 78-98-8 | CASP3 | Homo sapiens | salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP3 protein] | decreases^reaction|increases^expression | 26577515 |
| 32 | 78-98-8 | CASP3 | Homo sapiens | sulforafan inhibits the reaction [Pyruvaldehyde results in increased activity of CASP3 protein] | decreases^reaction|increases^activity | 25933243 |
| 33 | 78-98-8 | CASP3 | Mus musculus | resveratrol inhibits the reaction [Pyruvaldehyde results in increased activity of CASP3 protein] | decreases^reaction|increases^activity | 21793156 |
| 34 | 78-98-8 | CASP3 | Rattus norvegicus | Pyruvaldehyde results in increased expression of CASP3 protein modified form | increases^expression | 20621070 |
| 35 | 78-98-8 | CASP9 | Homo sapiens | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein]] | decreases^reaction|increases^expression | 26577515 |
| 36 | 78-98-8 | CASP9 | Homo sapiens | Pyruvaldehyde results in increased expression of CASP9 protein | increases^expression | 26577515 |
| 37 | 78-98-8 | CASP9 | Homo sapiens | salvin inhibits the reaction [Pyruvaldehyde results in increased expression of CASP9 protein] | decreases^reaction|increases^expression | 26577515 |
| 38 | 78-98-8 | CCL2 | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of CCL2 protein] | decreases^reaction|increases^expression | 22101032 |
| 39 | 78-98-8 | CCL2 | Mus musculus | Pyruvaldehyde results in increased expression of CCL2 protein | increases^expression | 22101032 |
| 40 | 78-98-8 | COL3A1 | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of COL3A1 protein] | decreases^reaction|increases^expression | 22101032 |
| 41 | 78-98-8 | COL3A1 | Mus musculus | Pyruvaldehyde results in increased expression of COL3A1 protein | increases^expression | 22101032 |
| 42 | 78-98-8 | CP | Homo sapiens | bathocuproine inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] | affects^binding|decreases^reaction|increases^reaction | 16756764 |
| 43 | 78-98-8 | CP | Homo sapiens | Ditiocarb inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] | affects^binding|decreases^reaction|increases^reaction | 16756764 |
| 44 | 78-98-8 | CP | Homo sapiens | formic acid inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] | affects^binding|decreases^reaction|increases^reaction | 16756764 |
| 45 | 78-98-8 | CP | Homo sapiens | Pyruvaldehyde promotes the reaction [CP protein binds to CP protein] | affects^binding|increases^reaction | 16756764 |
| 46 | 78-98-8 | CP | Homo sapiens | Pyruvaldehyde results in decreased activity of CP protein | decreases^activity | 16756764 |
| 47 | 78-98-8 | CP | Homo sapiens | Sodium Azide inhibits the reaction [Pyruvaldehyde promotes the reaction [CP protein binds to CP protein]] | affects^binding|decreases^reaction|increases^reaction | 16756764 |
| 48 | 78-98-8 | CTSB | Bos taurus | Pyruvaldehyde results in decreased activity of CTSB protein | decreases^activity | 16671891 |
| 49 | 78-98-8 | CTSL | Bos taurus | Pyruvaldehyde results in decreased activity of CTSL protein | decreases^activity | 16671891 |
| 50 | 78-98-8 | CTSS | Homo sapiens | Pyruvaldehyde results in decreased activity of CTSS protein | decreases^activity | 16671891 |
| 51 | 78-98-8 | CXCL8 | Homo sapiens | Pyruvaldehyde analog affects the expression of CXCL8 mRNA | affects^expression | 20200221 |
| 52 | 78-98-8 | FN1 | Rattus norvegicus | diphenyleneiodonium inhibits the reaction [Pyruvaldehyde results in increased expression of FN1 mRNA] | decreases^reaction|increases^expression | 17635749 |
| 53 | 78-98-8 | FN1 | Rattus norvegicus | manumycin inhibits the reaction [Pyruvaldehyde results in increased expression of FN1 mRNA] | decreases^reaction|increases^expression | 17635749 |
| 54 | 78-98-8 | FN1 | Rattus norvegicus | Pyruvaldehyde results in increased expression of FN1 mRNA | increases^expression | 17635749 |
| 55 | 78-98-8 | FN1 | Rattus norvegicus | SB 203580 inhibits the reaction [Pyruvaldehyde results in increased expression of FN1 mRNA] | decreases^reaction|increases^expression | 17635749 |
| 56 | 78-98-8 | GLO1 | Homo sapiens | GLO1 protein affects the reaction [Pyruvaldehyde binds to HSPB1 protein] | affects^binding|affects^reaction | 20093988 |
| 57 | 78-98-8 | GLO1 | Homo sapiens | GLO1 protein affects the susceptibility to Pyruvaldehyde | affects^response to substance | 20093988 |
| 58 | 78-98-8 | GLO1 | Homo sapiens | NFE2L2 protein affects the reaction [resveratrol affects the reaction [Pyruvaldehyde affects the expression of GLO1 protein]] | affects^expression|affects^reaction | 22917016 |
| 59 | 78-98-8 | GLO1 | Homo sapiens | Pyruvaldehyde affects the expression of GLO1 protein | affects^expression | 22917016 |
| 60 | 78-98-8 | GLO1 | Homo sapiens | Pyruvaldehyde results in decreased expression of GLO1 protein | decreases^expression | 25933243 |
| 61 | 78-98-8 | GLO1 | Homo sapiens | resveratrol affects the reaction [Pyruvaldehyde affects the expression of GLO1 protein] | affects^expression|affects^reaction | 22917016 |
| 62 | 78-98-8 | GLO1 | Homo sapiens | rosiglitazone affects the reaction [Pyruvaldehyde affects the expression of GLO1 protein] | affects^expression|affects^reaction | 22917016 |
| 63 | 78-98-8 | GLO1 | Homo sapiens | sulforafan inhibits the reaction [Pyruvaldehyde results in decreased expression of GLO1 protein] | decreases^expression|decreases^reaction | 25933243 |
| 64 | 78-98-8 | GLO1 | Mus musculus | honokiol inhibits the reaction [Pyruvaldehyde results in decreased activity of GLO1 protein] | decreases^activity|decreases^reaction | 26723916 |
| 65 | 78-98-8 | GLO1 | Mus musculus | pimagedine inhibits the reaction [Pyruvaldehyde results in decreased activity of GLO1 protein] | decreases^activity|decreases^reaction | 26723916 |
| 66 | 78-98-8 | GLO1 | Mus musculus | Pyruvaldehyde results in decreased activity of GLO1 protein | decreases^activity | 26723916 |
| 67 | 78-98-8 | GLO1 | GLO1 protein inhibits the reaction [[Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein]] | affects^binding|affects^cotreatment|decreases^activity|decreases^reaction|increases^reaction | 18227068 | |
| 68 | 78-98-8 | GOT1 | Sus scrofa | Pyruvaldehyde results in decreased activity of GOT1 protein | decreases^activity | 12559987 |
| 69 | 78-98-8 | GSR | Bos taurus | Pyruvaldehyde results in decreased activity of GSR protein | decreases^activity | 9175718 |
| 70 | 78-98-8 | GSTA5 | Rattus norvegicus | GSTA5 protein results in increased susceptibility to Pyruvaldehyde | increases^response to substance | 12076520 |
| 71 | 78-98-8 | HIF1A | Mus musculus | [Glucose co-treated with Oxygen deficiency] promotes the reaction [Pyruvaldehyde binds to and results in decreased activity of HIF1A protein] | affects^binding|affects^cotreatment|decreases^activity|increases^reaction | 18227068 |
| 72 | 78-98-8 | HIF1A | Mus musculus | Pyruvaldehyde binds to and results in decreased activity of HIF1A protein | affects^binding|decreases^activity | 18227068 |
| 73 | 78-98-8 | HIF1A | Reactive Oxygen Species promotes the reaction [Pyruvaldehyde binds to HIF1A protein] | affects^binding|increases^reaction | 18227068 | |
| 74 | 78-98-8 | HMOX1 | Homo sapiens | Acetylcysteine affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein] | affects^expression|affects^reaction | 22917016 |
| 75 | 78-98-8 | HMOX1 | Homo sapiens | NFE2L2 protein affects the reaction [resveratrol affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein]] | affects^expression|affects^reaction | 22917016 |
| 76 | 78-98-8 | HMOX1 | Homo sapiens | Pyruvaldehyde affects the expression of HMOX1 protein | affects^expression | 22917016 |
| 77 | 78-98-8 | HMOX1 | Homo sapiens | resveratrol affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein] | affects^expression|affects^reaction | 22917016 |
| 78 | 78-98-8 | HMOX1 | Homo sapiens | rosiglitazone affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein] | affects^expression|affects^reaction | 22917016 |
| 79 | 78-98-8 | HRAS | Rattus norvegicus | Pyruvaldehyde results in increased activity of HRAS protein | increases^activity | 17635749 |
| 80 | 78-98-8 | HSPB1 | Homo sapiens | Pyruvaldehyde binds to HSPB1 protein | affects^binding | 20093988 |
| 81 | 78-98-8 | IL1B | Rattus norvegicus | monascin inhibits the reaction [Pyruvaldehyde results in increased expression of IL1B protein] | decreases^reaction|increases^expression | 23954466 |
| 82 | 78-98-8 | IL1B | Rattus norvegicus | PPARG mutant form inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of IL1B protein]] | decreases^reaction|increases^expression | 23954466 |
| 83 | 78-98-8 | IL1B | Rattus norvegicus | PPARG mutant form inhibits the reaction [rosiglitazone inhibits the reaction [Pyruvaldehyde results in increased expression of IL1B protein]] | decreases^reaction|increases^expression | 23954466 |
| 84 | 78-98-8 | IL1B | Rattus norvegicus | Pyruvaldehyde results in increased expression of IL1B protein | increases^expression | 23954466 |
| 85 | 78-98-8 | IL1B | Rattus norvegicus | rosiglitazone inhibits the reaction [Pyruvaldehyde results in increased expression of IL1B protein] | decreases^reaction|increases^expression | 23954466 |
| 86 | 78-98-8 | IL6 | Homo sapiens | Pyruvaldehyde analog affects the expression of IL6 mRNA | affects^expression | 20200221 |
| 87 | 78-98-8 | IL6 | Mus musculus | honokiol affects the reaction [Pyruvaldehyde results in increased expression of IL6 protein] | affects^reaction|increases^expression | 26723916 |
| 88 | 78-98-8 | IL6 | Mus musculus | pimagedine inhibits the reaction [Pyruvaldehyde results in increased expression of IL6 protein] | decreases^reaction|increases^expression | 26723916 |
| 89 | 78-98-8 | IL6 | Mus musculus | Pyruvaldehyde results in increased expression of IL6 protein | increases^expression | 26723916 |
| 90 | 78-98-8 | INS1 | Rattus norvegicus | Pyruvaldehyde results in decreased secretion of and results in decreased expression of INS1 protein | decreases^expression|decreases^secretion | 23954466 |
| 91 | 78-98-8 | MAPT | Mus musculus | Pyruvaldehyde promotes the reaction [MAPT protein binds to MAPT protein] | affects^binding|increases^reaction | 17082178 |
| 92 | 78-98-8 | NFE2L2 | Homo sapiens | NFE2L2 protein affects the reaction [resveratrol inhibits the reaction [Pyruvaldehyde results in increased expression of PTPN1 protein]] | affects^reaction|decreases^reaction|increases^expression | 22917016 |
| 93 | 78-98-8 | NFE2L2 | Homo sapiens | NFE2L2 protein affects the susceptibility to Pyruvaldehyde | affects^response to substance | 28263721 |
| 94 | 78-98-8 | NFE2L2 | Homo sapiens | [resveratrol results in increased activity of NFE2L2 protein] which results in decreased susceptibility to Pyruvaldehyde | decreases^response to substance|increases^activity | 23954466 |
| 95 | 78-98-8 | NFE2L2 | NFE2L2 protein results in decreased susceptibility to Pyruvaldehyde | decreases^response to substance | 23954466 | |
| 96 | 78-98-8 | NOS2 | Rattus norvegicus | NOS2 protein affects the susceptibility to Pyruvaldehyde | affects^response to substance | 20621070 |
| 97 | 78-98-8 | NOS2 | Rattus norvegicus | pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased expression of NOS2 protein] | decreases^reaction|increases^expression | 20621070 |
| 98 | 78-98-8 | NOS2 | Rattus norvegicus | Pyruvaldehyde results in increased expression of NOS2 protein | increases^expression | 20621070 |
| 99 | 78-98-8 | NQO1 | Homo sapiens | Pyruvaldehyde results in increased expression of NQO1 mRNA | increases^expression | 25451587 |
| 100 | 78-98-8 | NRF1 | Rattus norvegicus | monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA] | decreases^reaction|increases^expression | 23331247 |
| 101 | 78-98-8 | NRF1 | Rattus norvegicus | Pyruvaldehyde results in increased expression of NRF1 mRNA | increases^expression | 23331247 |
| 102 | 78-98-8 | NRF1 | Rattus norvegicus | Silymarin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA] | decreases^reaction|increases^expression | 23331247 |
| 103 | 78-98-8 | NRF1 | Rattus norvegicus | Tretinoin inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of NRF1 mRNA]] | decreases^reaction|increases^expression | 23331247 |
| 104 | 78-98-8 | NTRK2 | Homo sapiens | Pyruvaldehyde results in decreased expression of NTRK2 protein | decreases^expression | 25933243 |
| 105 | 78-98-8 | NTRK2 | Homo sapiens | sulforafan inhibits the reaction [Pyruvaldehyde results in decreased expression of NTRK2 protein] | decreases^expression|decreases^reaction | 25933243 |
| 106 | 78-98-8 | PECAM1 | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of PECAM1 protein] | decreases^reaction|increases^expression | 22101032 |
| 107 | 78-98-8 | PECAM1 | Mus musculus | Pyruvaldehyde results in increased expression of PECAM1 protein | increases^expression | 22101032 |
| 108 | 78-98-8 | PON1 | Homo sapiens | Pyruvaldehyde results in decreased activity of PON1 protein | decreases^activity | 15375178 |
| 109 | 78-98-8 | PPARG | Rattus norvegicus | PPARG mutant form inhibits the reaction [monascin inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein]] | decreases^reaction|increases^expression | 23954466 |
| 110 | 78-98-8 | PPARG | Rattus norvegicus | PPARG mutant form inhibits the reaction [rosiglitazone inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein]] | decreases^reaction|increases^expression | 23954466 |
| 111 | 78-98-8 | PPARGC1A | Mus musculus | [Pyruvaldehyde co-treated with honokiol] results in increased expression of PPARGC1A protein | affects^cotreatment|increases^expression | 26723916 |
| 112 | 78-98-8 | PPARGC1A | Mus musculus | [Pyruvaldehyde co-treated with pimagedine] results in increased expression of PPARGC1A protein | affects^cotreatment|increases^expression | 26723916 |
| 113 | 78-98-8 | PTGS1 | Ovis aries | Aspirin promotes the reaction [Pyruvaldehyde results in decreased activity of PTGS1 protein] | decreases^activity|increases^reaction | 27083140 |
| 114 | 78-98-8 | PTGS1 | Ovis aries | Pyruvaldehyde results in decreased activity of PTGS1 protein | decreases^activity | 27083140 |
| 115 | 78-98-8 | PTPN1 | Homo sapiens | Acetylcysteine inhibits the reaction [Pyruvaldehyde results in increased expression of PTPN1 protein] | decreases^reaction|increases^expression | 22917016 |
| 116 | 78-98-8 | PTPN1 | Homo sapiens | Pyruvaldehyde results in increased expression of PTPN1 protein | increases^expression | 22917016 |
| 117 | 78-98-8 | PTPN1 | Homo sapiens | rosiglitazone inhibits the reaction [Pyruvaldehyde results in increased expression of PTPN1 protein] | decreases^reaction|increases^expression | 22917016 |
| 118 | 78-98-8 | RELA | Rattus norvegicus | pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased activity of RELA protein] | decreases^reaction|increases^activity | 20621070 |
| 119 | 78-98-8 | RELA | Rattus norvegicus | Pyruvaldehyde results in increased activity of RELA protein | increases^activity | 20621070 |
| 120 | 78-98-8 | TGFB1 | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of TGFB1 protein] | decreases^reaction|increases^expression | 22101032 |
| 121 | 78-98-8 | TGFB1 | Mus musculus | Pyruvaldehyde results in increased expression of TGFB1 protein | increases^expression | 22101032 |
| 122 | 78-98-8 | TGFB1 | Rattus norvegicus | diphenyleneiodonium inhibits the reaction [Pyruvaldehyde results in increased expression of TGFB1 mRNA] | decreases^reaction|increases^expression | 17635749 |
| 123 | 78-98-8 | TGFB1 | Rattus norvegicus | diphenyleneiodonium inhibits the reaction [Pyruvaldehyde results in increased expression of TGFB1 protein] | decreases^reaction|increases^expression | 17635749 |
| 124 | 78-98-8 | TGFB1 | Rattus norvegicus | Pyruvaldehyde results in increased expression of TGFB1 mRNA | increases^expression | 17635749 |
| 125 | 78-98-8 | TNF | Mus musculus | honokiol inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein] | decreases^reaction|increases^expression | 26723916 |
| 126 | 78-98-8 | TNF | Mus musculus | pimagedine inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein] | decreases^reaction|increases^expression | 26723916 |
| 127 | 78-98-8 | TNF | Mus musculus | Pyruvaldehyde results in increased expression of TNF protein | increases^expression | 26723916 |
| 128 | 78-98-8 | TNF | Rattus norvegicus | monascin inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein] | decreases^reaction|increases^expression | 23954466 |
| 129 | 78-98-8 | TNF | Rattus norvegicus | rosiglitazone inhibits the reaction [Pyruvaldehyde results in increased expression of TNF protein] | decreases^reaction|increases^expression | 23954466 |
| 130 | 78-98-8 | TRPA1 | Homo sapiens | Pyruvaldehyde results in increased activity of TRPA1 protein | increases^activity | 22863862 |
| 131 | 78-98-8 | TRPA1 | Homo sapiens | [Pyruvaldehyde results in increased activity of TRPA1 protein] which results in increased transport of Calcium | increases^activity|increases^transport | 22863862 |
| 132 | 78-98-8 | VCAM1 | Rattus norvegicus | Pyruvaldehyde results in increased expression of VCAM1 mRNA | increases^expression | 23331247 |
| 133 | 78-98-8 | VCAM1 | Rattus norvegicus | Silymarin inhibits the reaction [Pyruvaldehyde results in increased expression of VCAM1 mRNA] | decreases^reaction|increases^expression | 23331247 |
| 134 | 78-98-8 | VEGFA | Mus musculus | epigallocatechin gallate inhibits the reaction [Pyruvaldehyde results in increased expression of VEGFA protein] | decreases^reaction|increases^expression | 22101032 |
| 135 | 78-98-8 | VEGFA | Mus musculus | Pyruvaldehyde results in increased expression of VEGFA protein | increases^expression | 22101032 |
| Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
|---|---|---|---|---|---|
| 1 | 78-98-8 | Acetylformaldehyde |
Compound Image
2D Structure
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