CSIR CIMAP AROMA | Compound Details

Allyl isosulfocyanate Details

: IUPAC Name

Allylisothiocyanate

:Chemical Class

:CAS Registry Number

57-06-7

:Description

:Fragrance Type

pungent

Physical and Chemical properties

PUBCHEM ID	5971
Molecular Weight (g/mol)	99.157
Molecular Formula	C4H5NS
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
IUPAC Name	Allylisothiocyanate
Canonical SMILES	C=CCN=C=S
PUBCHEM IUPAC INCHIKEY	ZOJBYZNEUISWFT-UHFFFAOYSA-N
Solubility Level	4
Vapour Pressure	1.2

Absorption and Metabolism information

XLOGP3 AA	NA
CACTVS TPSA	26.3
BBB Level	1
Absorption Level	0
EXT PPB#Prediction	0
AlogP98	1.629
EXT CYP2D6#Prediction	0

Toxicological Information

Mouse Female FDA	Single-Carcinogen
Mouse Male FDA	Multi-Carcinogen
Rat Female FDA	Multi-Carcinogen
Rat Male FDA	Non-Carcinogen
Ames Prediction	Non-Mutagen
Developmental / Reproductive Toxicity	Toxic
Rat Oral LD50	0.108077
Ocular Irritancy	Severe
Hepatotoxic#Prediction	1
Effected Human Genes	NA

Ecological Information

Aerobic Biodegradability Prediction	Non-Degradable

Hazard(s) Identification

Physical hazards	not classified
Health hazards	Mild
Environmental hazards	not classified

About Table Headings

Compound Biological Activity

Serial No.	Cas No	Gene Symbol	Organism	Interaction	Interaction Actions	PubMed Id
1	57-06-7	ACTA2	Mus musculus	allyl isothiocyanate results in decreased expression of ACTA2 mRNA	decreases^expression	24036144
2	57-06-7	AGER	Mus musculus	allyl isothiocyanate results in decreased expression of AGER mRNA	decreases^expression	24036144
3	57-06-7	AIF1	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of AIF1 protein]	decreases^reaction\|increases^expression	27241356
4	57-06-7	BDKRB2	Homo sapiens	BDKRB2 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	increases^activity\|increases^reaction	17571167
5	57-06-7	CAT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	25744308
6	57-06-7	CAT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	27241356
7	57-06-7	CDKN1A	Homo sapiens	allyl isothiocyanate results in increased expression of CDKN1A mRNA	increases^expression	17937621
8	57-06-7	COL1A1	Mus musculus	allyl isothiocyanate results in decreased expression of COL1A1 mRNA	decreases^expression	24036144
9	57-06-7	CYP2B10	Mus musculus	allyl isothiocyanate inhibits the reaction [[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with NR1I3 protein] results in increased expression of CYP2B10 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
10	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of CYP2B6 protein]	decreases^reaction\|increases^activity	25069801
11	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]	decreases^reaction\|increases^expression	25069801
12	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 protein]	decreases^reaction\|increases^expression	25069801
13	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
14	57-06-7	CYP3A2	Rattus norvegicus	allyl isothiocyanate results in decreased activity of CYP3A2 protein	decreases^activity	22664424
15	57-06-7	CYP3A2	Rattus norvegicus	allyl isothiocyanate results in decreased expression of CYP3A2 mRNA	decreases^expression	22664424
16	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
17	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
18	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
19	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
20	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
21	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
22	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
23	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
24	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
25	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
26	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
27	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]	decreases^reaction\|increases^activity	25069801
28	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
29	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]	decreases^reaction\|increases^expression	25069801
30	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
31	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
32	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
33	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate results in decreased activity of CYP3A4 protein	decreases^activity	25069801
34	57-06-7	CYP3A4	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
35	57-06-7	F2RL1	Homo sapiens	edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]	decreases^reaction\|increases^activity\|increases^reaction	17571167
36	57-06-7	F2RL1	Homo sapiens	F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	increases^activity\|increases^reaction	17571167
37	57-06-7	F2RL1	Homo sapiens	Phosphatidylinositol 4,5-Diphosphate inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]	decreases^reaction\|increases^activity\|increases^reaction	17571167
38	57-06-7	GADD45A	Homo sapiens	allyl isothiocyanate results in increased expression of GADD45A mRNA	increases^expression	17937621
39	57-06-7	GCLC	Mus musculus	allyl isothiocyanate results in increased activity of GCLC protein	increases^activity	24036144
40	57-06-7	GCLC	Mus musculus	allyl isothiocyanate results in increased expression of GCLC mRNA	increases^expression	24036144
41	57-06-7	GCLC	Mus musculus	NFE2L2 protein affects the reaction [allyl isothiocyanate results in increased expression of GCLC mRNA]	affects^reaction\|increases^expression	24036144
42	57-06-7	GPT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]	decreases^reaction\|increases^activity	27241356
43	57-06-7	GSR	Homo sapiens	allyl isothiocyanate results in decreased activity of GSR protein	decreases^activity	17937621
44	57-06-7	GSR	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]	decreases^activity\|decreases^reaction	25744308
45	57-06-7	GSR	Rattus norvegicus	allyl isothiocyanate results in increased activity of GSR protein	increases^activity	22664424
46	57-06-7	GSTA3	Mus musculus	allyl isothiocyanate results in increased activity of GSTA3 promoter	increases^activity	19232536
47	57-06-7	HMOX1	Mus musculus	allyl isothiocyanate results in increased expression of HMOX1 protein	increases^expression	23942037
48	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 protein]	decreases^expression\|decreases^reaction	27241356
49	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate results in increased activity of HMOX1 protein	increases^activity	22664424
50	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate results in increased expression of HMOX1 mRNA	increases^expression	22664424
51	57-06-7	MAPK1	Homo sapiens	[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK1 protein	affects^cotreatment\|increases^phosphorylation	23994502
52	57-06-7	MAPK1	Homo sapiens	Ruthenium Red inhibits the reaction [[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK1 protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	23994502
53	57-06-7	MAPK3	Homo sapiens	[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK3 protein	affects^cotreatment\|increases^phosphorylation	23994502
54	57-06-7	MAPK3	Homo sapiens	Ruthenium Red inhibits the reaction [[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK3 protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	23994502
55	57-06-7	NDRG1	Homo sapiens	allyl isothiocyanate results in increased expression of NDRG1 mRNA	increases^expression	17937621
56	57-06-7	NFE2L2	Mus musculus	allyl isothiocyanate results in increased activity of NFE2L2 protein	increases^activity	24036144
57	57-06-7	NFE2L2	Mus musculus	NFE2L2 protein promotes the reaction [sulforafan results in decreased susceptibility to allyl isothiocyanate]	decreases^response to substance\|increases^reaction	20932822
58	57-06-7	NFE2L2	Rattus norvegicus	allyl isothiocyanate results in increased expression of NFE2L2 protein	increases^expression	22664424
59	57-06-7	NQO1	Rattus norvegicus	allyl isothiocyanate results in increased activity of NQO1 protein	increases^activity	22664424
60	57-06-7	NQO1	Rattus norvegicus	allyl isothiocyanate results in increased expression of NQO1 mRNA	increases^expression	22664424
61	57-06-7	NR1I2		allyl isothiocyanate binds to and results in decreased activity of NR1I2 protein	affects^binding\|decreases^activity	25069801
62	57-06-7	NR1I3		allyl isothiocyanate binds to and results in decreased activity of NR1I3 protein	affects^binding\|decreases^activity	25069801
63	57-06-7	PDGFRB	Mus musculus	allyl isothiocyanate results in decreased expression of PDGFRB mRNA	decreases^expression	24036144
64	57-06-7	TNF	Mus musculus	allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]	decreases^reaction\|increases^expression	28483571
65	57-06-7	TNF	Mus musculus	allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]	decreases^reaction\|increases^expression	28483571
66	57-06-7	TNF	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]	decreases^reaction\|increases^expression	27241356
67	57-06-7	TRPA1	Anolis carolinensis	allyl isothiocyanate results in increased activity of TRPA1 protein	increases^activity	22791718
68	57-06-7	TRPA1	Homo sapiens	Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]	decreases^reaction\|increases^activity\|increases^uptake	27738742
69	57-06-7	TRPA1	Homo sapiens	[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium	increases^activity\|increases^uptake	27738742
70	57-06-7	TRPA1	Homo sapiens	TRPA1 mRNA affects the susceptibility to allyl isothiocyanate	affects^response to substance	19507004
71	57-06-7	TRPA1	Mus musculus	2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	21689654
72	57-06-7	TRPA1	Mus musculus	allyl isothiocyanate binds to and results in increased activity of TRPA1 protein	affects^binding\|increases^activity	15843607\|17825279
73	57-06-7	TRPA1	Mus musculus	Amiloride inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
74	57-06-7	TRPA1	Mus musculus	Gadolinium inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
75	57-06-7	TRPA1	Mus musculus	Gentamicins inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
76	57-06-7	TRPA1	Mus musculus	Ruthenium Red inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
77	57-06-7	TRPA1	Mus musculus	TRPA1 affects the susceptibility to allyl isothiocyanate	affects^response to substance	20442136\|20720158
78	57-06-7	TRPA1	Rattus norvegicus	[allyl isothiocyanate binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium	affects^binding\|increases^activity\|increases^transport	20086034
79	57-06-7	TRPV1	Mus musculus	TRPV1 affects the susceptibility to allyl isothiocyanate	affects^response to substance	21430076
80	57-06-7	TXNRD1	Homo sapiens	allyl isothiocyanate results in decreased activity of TXNRD1 protein	decreases^activity	17937621
81	57-06-7	ACTA2	Mus musculus	allyl isothiocyanate results in decreased expression of ACTA2 mRNA	decreases^expression	24036144
82	57-06-7	AGER	Mus musculus	allyl isothiocyanate results in decreased expression of AGER mRNA	decreases^expression	24036144
83	57-06-7	AIF1	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of AIF1 protein]	decreases^reaction\|increases^expression	27241356
84	57-06-7	BDKRB2	Homo sapiens	BDKRB2 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	increases^activity\|increases^reaction	17571167
85	57-06-7	CAT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	25744308
86	57-06-7	CAT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	27241356
87	57-06-7	CDKN1A	Homo sapiens	allyl isothiocyanate results in increased expression of CDKN1A mRNA	increases^expression	17937621
88	57-06-7	COL1A1	Mus musculus	allyl isothiocyanate results in decreased expression of COL1A1 mRNA	decreases^expression	24036144
89	57-06-7	CYP2B10	Mus musculus	allyl isothiocyanate inhibits the reaction [[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with NR1I3 protein] results in increased expression of CYP2B10 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
90	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of CYP2B6 protein]	decreases^reaction\|increases^activity	25069801
91	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]	decreases^reaction\|increases^expression	25069801
92	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 protein]	decreases^reaction\|increases^expression	25069801
93	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
94	57-06-7	CYP3A2	Rattus norvegicus	allyl isothiocyanate results in decreased activity of CYP3A2 protein	decreases^activity	22664424
95	57-06-7	CYP3A2	Rattus norvegicus	allyl isothiocyanate results in decreased expression of CYP3A2 mRNA	decreases^expression	22664424
96	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
97	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
98	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
99	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
100	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
101	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
102	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
103	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
104	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
105	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
106	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
107	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]	decreases^reaction\|increases^activity	25069801
108	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
109	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]	decreases^reaction\|increases^expression	25069801
110	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
111	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
112	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
113	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate results in decreased activity of CYP3A4 protein	decreases^activity	25069801
114	57-06-7	CYP3A4	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
115	57-06-7	F2RL1	Homo sapiens	edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]	decreases^reaction\|increases^activity\|increases^reaction	17571167
116	57-06-7	F2RL1	Homo sapiens	F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	increases^activity\|increases^reaction	17571167
117	57-06-7	F2RL1	Homo sapiens	Phosphatidylinositol 4,5-Diphosphate inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]	decreases^reaction\|increases^activity\|increases^reaction	17571167
118	57-06-7	GADD45A	Homo sapiens	allyl isothiocyanate results in increased expression of GADD45A mRNA	increases^expression	17937621
119	57-06-7	GCLC	Mus musculus	allyl isothiocyanate results in increased activity of GCLC protein	increases^activity	24036144
120	57-06-7	GCLC	Mus musculus	allyl isothiocyanate results in increased expression of GCLC mRNA	increases^expression	24036144
121	57-06-7	GCLC	Mus musculus	NFE2L2 protein affects the reaction [allyl isothiocyanate results in increased expression of GCLC mRNA]	affects^reaction\|increases^expression	24036144
122	57-06-7	GPT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]	decreases^reaction\|increases^activity	27241356
123	57-06-7	GSR	Homo sapiens	allyl isothiocyanate results in decreased activity of GSR protein	decreases^activity	17937621
124	57-06-7	GSR	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]	decreases^activity\|decreases^reaction	25744308
125	57-06-7	GSR	Rattus norvegicus	allyl isothiocyanate results in increased activity of GSR protein	increases^activity	22664424
126	57-06-7	GSTA3	Mus musculus	allyl isothiocyanate results in increased activity of GSTA3 promoter	increases^activity	19232536
127	57-06-7	HMOX1	Mus musculus	allyl isothiocyanate results in increased expression of HMOX1 protein	increases^expression	23942037
128	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 protein]	decreases^expression\|decreases^reaction	27241356
129	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate results in increased activity of HMOX1 protein	increases^activity	22664424
130	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate results in increased expression of HMOX1 mRNA	increases^expression	22664424
131	57-06-7	MAPK1	Homo sapiens	[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK1 protein	affects^cotreatment\|increases^phosphorylation	23994502
132	57-06-7	MAPK1	Homo sapiens	Ruthenium Red inhibits the reaction [[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK1 protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	23994502
133	57-06-7	MAPK3	Homo sapiens	[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK3 protein	affects^cotreatment\|increases^phosphorylation	23994502
134	57-06-7	MAPK3	Homo sapiens	Ruthenium Red inhibits the reaction [[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK3 protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	23994502
135	57-06-7	NDRG1	Homo sapiens	allyl isothiocyanate results in increased expression of NDRG1 mRNA	increases^expression	17937621
136	57-06-7	NFE2L2	Mus musculus	allyl isothiocyanate results in increased activity of NFE2L2 protein	increases^activity	24036144
137	57-06-7	NFE2L2	Mus musculus	NFE2L2 protein promotes the reaction [sulforafan results in decreased susceptibility to allyl isothiocyanate]	decreases^response to substance\|increases^reaction	20932822
138	57-06-7	NFE2L2	Rattus norvegicus	allyl isothiocyanate results in increased expression of NFE2L2 protein	increases^expression	22664424
139	57-06-7	NQO1	Rattus norvegicus	allyl isothiocyanate results in increased activity of NQO1 protein	increases^activity	22664424
140	57-06-7	NQO1	Rattus norvegicus	allyl isothiocyanate results in increased expression of NQO1 mRNA	increases^expression	22664424
141	57-06-7	NR1I2		allyl isothiocyanate binds to and results in decreased activity of NR1I2 protein	affects^binding\|decreases^activity	25069801
142	57-06-7	NR1I3		allyl isothiocyanate binds to and results in decreased activity of NR1I3 protein	affects^binding\|decreases^activity	25069801
143	57-06-7	PDGFRB	Mus musculus	allyl isothiocyanate results in decreased expression of PDGFRB mRNA	decreases^expression	24036144
144	57-06-7	TNF	Mus musculus	allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]	decreases^reaction\|increases^expression	28483571
145	57-06-7	TNF	Mus musculus	allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]	decreases^reaction\|increases^expression	28483571
146	57-06-7	TNF	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]	decreases^reaction\|increases^expression	27241356
147	57-06-7	TRPA1	Anolis carolinensis	allyl isothiocyanate results in increased activity of TRPA1 protein	increases^activity	22791718
148	57-06-7	TRPA1	Homo sapiens	Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]	decreases^reaction\|increases^activity\|increases^uptake	27738742
149	57-06-7	TRPA1	Homo sapiens	[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium	increases^activity\|increases^uptake	27738742
150	57-06-7	TRPA1	Homo sapiens	TRPA1 mRNA affects the susceptibility to allyl isothiocyanate	affects^response to substance	19507004
151	57-06-7	TRPA1	Mus musculus	2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	21689654
152	57-06-7	TRPA1	Mus musculus	allyl isothiocyanate binds to and results in increased activity of TRPA1 protein	affects^binding\|increases^activity	15843607\|17825279
153	57-06-7	TRPA1	Mus musculus	Amiloride inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
154	57-06-7	TRPA1	Mus musculus	Gadolinium inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
155	57-06-7	TRPA1	Mus musculus	Gentamicins inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
156	57-06-7	TRPA1	Mus musculus	Ruthenium Red inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
157	57-06-7	TRPA1	Mus musculus	TRPA1 affects the susceptibility to allyl isothiocyanate	affects^response to substance	20442136\|20720158
158	57-06-7	TRPA1	Rattus norvegicus	[allyl isothiocyanate binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium	affects^binding\|increases^activity\|increases^transport	20086034
159	57-06-7	TRPV1	Mus musculus	TRPV1 affects the susceptibility to allyl isothiocyanate	affects^response to substance	21430076
160	57-06-7	TXNRD1	Homo sapiens	allyl isothiocyanate results in decreased activity of TXNRD1 protein	decreases^activity	17937621
161	57-06-7	ACTA2	Mus musculus	allyl isothiocyanate results in decreased expression of ACTA2 mRNA	decreases^expression	24036144
162	57-06-7	AGER	Mus musculus	allyl isothiocyanate results in decreased expression of AGER mRNA	decreases^expression	24036144
163	57-06-7	AIF1	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of AIF1 protein]	decreases^reaction\|increases^expression	27241356
164	57-06-7	BDKRB2	Homo sapiens	BDKRB2 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	increases^activity\|increases^reaction	17571167
165	57-06-7	CAT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	25744308
166	57-06-7	CAT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	27241356
167	57-06-7	CDKN1A	Homo sapiens	allyl isothiocyanate results in increased expression of CDKN1A mRNA	increases^expression	17937621
168	57-06-7	COL1A1	Mus musculus	allyl isothiocyanate results in decreased expression of COL1A1 mRNA	decreases^expression	24036144
169	57-06-7	CYP2B10	Mus musculus	allyl isothiocyanate inhibits the reaction [[1,4-bis(2-(3,5-dichloropyridyloxy))benzene co-treated with NR1I3 protein] results in increased expression of CYP2B10 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
170	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased activity of CYP2B6 protein]	decreases^reaction\|increases^activity	25069801
171	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]	decreases^reaction\|increases^expression	25069801
172	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 protein]	decreases^reaction\|increases^expression	25069801
173	57-06-7	CYP2B6	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP2B6 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
174	57-06-7	CYP3A2	Rattus norvegicus	allyl isothiocyanate results in decreased activity of CYP3A2 protein	decreases^activity	22664424
175	57-06-7	CYP3A2	Rattus norvegicus	allyl isothiocyanate results in decreased expression of CYP3A2 mRNA	decreases^expression	22664424
176	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
177	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
178	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
179	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Nifedipine results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
180	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
181	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
182	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
183	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
184	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25069801
185	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [NR1I3 protein promotes the reaction [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime results in increased expression of CYP3A4 mRNA]]	decreases^reaction\|increases^expression\|increases^reaction	25069801
186	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
187	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased activity of CYP3A4 protein]	decreases^reaction\|increases^activity	25069801
188	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
189	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [Rifampin results in increased expression of CYP3A4 protein]	decreases^reaction\|increases^expression	25069801
190	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
191	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [SR 12813 results in increased expression of CYP3A4 mRNA]	decreases^reaction\|increases^expression	25069801
192	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
193	57-06-7	CYP3A4	Homo sapiens	allyl isothiocyanate results in decreased activity of CYP3A4 protein	decreases^activity	25069801
194	57-06-7	CYP3A4	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [[NR1I2 protein co-treated with Pregnenolone Carbonitrile] results in increased expression of CYP3A4 mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25069801
195	57-06-7	F2RL1	Homo sapiens	edelfosine inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]	decreases^reaction\|increases^activity\|increases^reaction	17571167
196	57-06-7	F2RL1	Homo sapiens	F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	increases^activity\|increases^reaction	17571167
197	57-06-7	F2RL1	Homo sapiens	Phosphatidylinositol 4,5-Diphosphate inhibits the reaction [F2RL1 protein promotes the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]]	decreases^reaction\|increases^activity\|increases^reaction	17571167
198	57-06-7	GADD45A	Homo sapiens	allyl isothiocyanate results in increased expression of GADD45A mRNA	increases^expression	17937621
199	57-06-7	GCLC	Mus musculus	allyl isothiocyanate results in increased activity of GCLC protein	increases^activity	24036144
200	57-06-7	GCLC	Mus musculus	allyl isothiocyanate results in increased expression of GCLC mRNA	increases^expression	24036144
201	57-06-7	GCLC	Mus musculus	NFE2L2 protein affects the reaction [allyl isothiocyanate results in increased expression of GCLC mRNA]	affects^reaction\|increases^expression	24036144
202	57-06-7	GPT	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]	decreases^reaction\|increases^activity	27241356
203	57-06-7	GSR	Homo sapiens	allyl isothiocyanate results in decreased activity of GSR protein	decreases^activity	17937621
204	57-06-7	GSR	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein]	decreases^activity\|decreases^reaction	25744308
205	57-06-7	GSR	Rattus norvegicus	allyl isothiocyanate results in increased activity of GSR protein	increases^activity	22664424
206	57-06-7	GSTA3	Mus musculus	allyl isothiocyanate results in increased activity of GSTA3 promoter	increases^activity	19232536
207	57-06-7	HMOX1	Mus musculus	allyl isothiocyanate results in increased expression of HMOX1 protein	increases^expression	23942037
208	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 protein]	decreases^expression\|decreases^reaction	27241356
209	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate results in increased activity of HMOX1 protein	increases^activity	22664424
210	57-06-7	HMOX1	Rattus norvegicus	allyl isothiocyanate results in increased expression of HMOX1 mRNA	increases^expression	22664424
211	57-06-7	MAPK1	Homo sapiens	[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK1 protein	affects^cotreatment\|increases^phosphorylation	23994502
212	57-06-7	MAPK1	Homo sapiens	Ruthenium Red inhibits the reaction [[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK1 protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	23994502
213	57-06-7	MAPK3	Homo sapiens	[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK3 protein	affects^cotreatment\|increases^phosphorylation	23994502
214	57-06-7	MAPK3	Homo sapiens	Ruthenium Red inhibits the reaction [[allyl isothiocyanate co-treated with TRPA1 protein] results in increased phosphorylation of MAPK3 protein]	affects^cotreatment\|decreases^reaction\|increases^phosphorylation	23994502
215	57-06-7	NDRG1	Homo sapiens	allyl isothiocyanate results in increased expression of NDRG1 mRNA	increases^expression	17937621
216	57-06-7	NFE2L2	Mus musculus	allyl isothiocyanate results in increased activity of NFE2L2 protein	increases^activity	24036144
217	57-06-7	NFE2L2	Mus musculus	NFE2L2 protein promotes the reaction [sulforafan results in decreased susceptibility to allyl isothiocyanate]	decreases^response to substance\|increases^reaction	20932822
218	57-06-7	NFE2L2	Rattus norvegicus	allyl isothiocyanate results in increased expression of NFE2L2 protein	increases^expression	22664424
219	57-06-7	NQO1	Rattus norvegicus	allyl isothiocyanate results in increased activity of NQO1 protein	increases^activity	22664424
220	57-06-7	NQO1	Rattus norvegicus	allyl isothiocyanate results in increased expression of NQO1 mRNA	increases^expression	22664424
221	57-06-7	NR1I2		allyl isothiocyanate binds to and results in decreased activity of NR1I2 protein	affects^binding\|decreases^activity	25069801
222	57-06-7	NR1I3		allyl isothiocyanate binds to and results in decreased activity of NR1I3 protein	affects^binding\|decreases^activity	25069801
223	57-06-7	PDGFRB	Mus musculus	allyl isothiocyanate results in decreased expression of PDGFRB mRNA	decreases^expression	24036144
224	57-06-7	TNF	Mus musculus	allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]	decreases^reaction\|increases^expression	28483571
225	57-06-7	TNF	Mus musculus	allyl isothiocyanate inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]	decreases^reaction\|increases^expression	28483571
226	57-06-7	TNF	Rattus norvegicus	allyl isothiocyanate inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]	decreases^reaction\|increases^expression	27241356
227	57-06-7	TRPA1	Anolis carolinensis	allyl isothiocyanate results in increased activity of TRPA1 protein	increases^activity	22791718
228	57-06-7	TRPA1	Homo sapiens	Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]	decreases^reaction\|increases^activity\|increases^uptake	27738742
229	57-06-7	TRPA1	Homo sapiens	[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium	increases^activity\|increases^uptake	27738742
230	57-06-7	TRPA1	Homo sapiens	TRPA1 mRNA affects the susceptibility to allyl isothiocyanate	affects^response to substance	19507004
231	57-06-7	TRPA1	Mus musculus	2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	21689654
232	57-06-7	TRPA1	Mus musculus	allyl isothiocyanate binds to and results in increased activity of TRPA1 protein	affects^binding\|increases^activity	15843607\|17825279
233	57-06-7	TRPA1	Mus musculus	Amiloride inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
234	57-06-7	TRPA1	Mus musculus	Gadolinium inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
235	57-06-7	TRPA1	Mus musculus	Gentamicins inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
236	57-06-7	TRPA1	Mus musculus	Ruthenium Red inhibits the reaction [allyl isothiocyanate results in increased activity of TRPA1 protein]	decreases^reaction\|increases^activity	15843607
237	57-06-7	TRPA1	Mus musculus	TRPA1 affects the susceptibility to allyl isothiocyanate	affects^response to substance	20442136\|20720158
238	57-06-7	TRPA1	Rattus norvegicus	[allyl isothiocyanate binds to and results in increased activity of TRPA1 protein] which results in increased transport of Calcium	affects^binding\|increases^activity\|increases^transport	20086034
239	57-06-7	TRPV1	Mus musculus	TRPV1 affects the susceptibility to allyl isothiocyanate	affects^response to substance	21430076
240	57-06-7	TXNRD1	Homo sapiens	allyl isothiocyanate results in decreased activity of TXNRD1 protein	decreases^activity	17937621

Serial No.	Activity Name	Details	References (PubMed)	Other details EPA (U.S)	Clinical Trials (U.S. NIH)
1				57-06-7	Allyl isosulfocyanate

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