CSIR CIMAP AROMA | Compound Details

Diallyl trisulfide Details

: IUPAC Name

3-(prop-2-enyltrisulfanyl)prop-1-ene

:Chemical Class

:CAS Registry Number

2050-87-5

:Description

:Fragrance Type

pungent

Physical and Chemical properties

PUBCHEM ID	16315
Molecular Weight (g/mol)	178.3386
Molecular Formula	C6H10S3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
IUPAC Name	3-(prop-2-enyltrisulfanyl)prop-1-ene
Canonical SMILES	C=CCSSSCC=C
PUBCHEM IUPAC INCHIKEY	UBAXRAHSPKWNCX-UHFFFAOYSA-N
Solubility Level
Vapour Pressure

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA
BBB Level
Absorption Level
EXT PPB#Prediction
AlogP98
EXT CYP2D6#Prediction

Toxicological Information

Mouse Female FDA
Mouse Male FDA
Rat Female FDA
Rat Male FDA
Ames Prediction
Developmental / Reproductive Toxicity
Rat Oral LD50
Ocular Irritancy
Hepatotoxic#Prediction
Effected Human Genes

Ecological Information

Aerobic Biodegradability Prediction

Hazard(s) Identification

Physical hazards	not classified
Health hazards
Environmental hazards	not classified

About Table Headings

Compound Biological Activity

Serial No.	Cas No	Gene Symbol	Organism	Interaction	Interaction Actions	PubMed Id
1	2050-87-5	ABCB1	Homo sapiens	diallyl trisulfide results in decreased expression of ABCB1 protein	decreases^expression	24788927
2	2050-87-5	ABCB1	Homo sapiens	diallyl trisulfide results in increased expression of ABCB1 mRNA	increases^expression	22397993
3	2050-87-5	ABCC1	Homo sapiens	diallyl trisulfide results in increased expression of ABCC1 mRNA	increases^expression	22397993
4	2050-87-5	ABCC3	Homo sapiens	diallyl trisulfide results in decreased expression of ABCC3 mRNA	decreases^expression	22397993
5	2050-87-5	ABCC4	Homo sapiens	diallyl trisulfide results in decreased expression of ABCC4 mRNA	decreases^expression	22397993
6	2050-87-5	ABCC4	Homo sapiens	diallyl trisulfide results in increased expression of ABCC4 mRNA	increases^expression	22397993
7	2050-87-5	ABCC6	Homo sapiens	diallyl trisulfide results in increased expression of ABCC6 mRNA	increases^expression	22397993
8	2050-87-5	ACTG1	Homo sapiens	diallyl trisulfide results in decreased expression of ACTG1 protein	decreases^expression	19550292
9	2050-87-5	AK2	Homo sapiens	diallyl trisulfide results in increased expression of AK2 protein	increases^expression	16344271
10	2050-87-5	AKT1	Homo sapiens	diallyl trisulfide results in decreased expression of AKT1 mRNA	decreases^expression	19823037
11	2050-87-5	AKT1	Homo sapiens	diallyl trisulfide results in decreased expression of AKT1 protein	decreases^expression	24415872
12	2050-87-5	ALDH1	Homo sapiens	diallyl trisulfide results in decreased activity of ALDH1 protein	decreases^activity	27129776
13	2050-87-5	ALDH1	Homo sapiens	FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased activity of ALDH1 protein]	decreases^activity\|decreases^reaction	27129776
14	2050-87-5	ALPL	Homo sapiens	diallyl trisulfide results in increased expression of ALPL protein	increases^expression	19550292
15	2050-87-5	ANXA1	Homo sapiens	diallyl trisulfide results in increased expression of ANXA1 mRNA	increases^expression	16344271
16	2050-87-5	ANXA1	Homo sapiens	diallyl trisulfide results in increased expression of ANXA1 protein	increases^expression	16344271
17	2050-87-5	AR	Homo sapiens	diallyl trisulfide results in decreased expression of AR mRNA	decreases^expression	19622577
18	2050-87-5	AR	Homo sapiens	diallyl trisulfide results in decreased expression of AR protein	decreases^expression	19622577
19	2050-87-5	ATP5H	Homo sapiens	diallyl trisulfide results in decreased expression of ATP5H protein	decreases^expression	16344271
20	2050-87-5	ATP5H	Homo sapiens	diallyl trisulfide results in increased expression of ATP5H protein	increases^expression	16344271
21	2050-87-5	BAK1	Homo sapiens	diallyl trisulfide results in increased activity of BAK1 protein	increases^activity	23412769
22	2050-87-5	BAK1	Homo sapiens	diallyl trisulfide results in increased expression of BAK1 protein	increases^expression	17513609
23	2050-87-5	BAK1	Homo sapiens	SOD2 protein inhibits the reaction [diallyl trisulfide results in increased activity of BAK1 protein]	decreases^reaction\|increases^activity	23412769
24	2050-87-5	BAX	Homo sapiens	diallyl trisulfide results in increased activity of BAX protein	increases^activity	23412769
25	2050-87-5	BAX	Homo sapiens	diallyl trisulfide results in increased expression of BAX mRNA	increases^expression	19823037\|24415872\|24460275
26	2050-87-5	BAX	Homo sapiens	diallyl trisulfide results in increased expression of BAX protein	increases^expression	19823037\|23754639\|24460275
27	2050-87-5	BBC3	Homo sapiens	diallyl trisulfide results in increased expression of BBC3 mRNA	increases^expression	24460275
28	2050-87-5	BBC3	Homo sapiens	diallyl trisulfide results in increased expression of BBC3 protein	increases^expression	24460275
29	2050-87-5	BCL2	Homo sapiens	Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]	decreases^expression\|decreases^reaction	22578287
30	2050-87-5	BCL2	Homo sapiens	diallyl trisulfide results in decreased expression of BCL2	decreases^expression	22595511
31	2050-87-5	BCL2	Homo sapiens	diallyl trisulfide results in decreased expression of BCL2 mRNA	decreases^expression	19823037\|24415872\|24460275
32	2050-87-5	BCL2	Homo sapiens	diallyl trisulfide results in decreased expression of BCL2 protein	decreases^expression	17513609\|20055834\|22578287\|23754639\|24415872\|24460275\|25205294
33	2050-87-5	BCL2L1	Homo sapiens	diallyl trisulfide results in decreased expression of BCL2L1 protein	decreases^expression	17513609\|20055834
34	2050-87-5	BID	Homo sapiens	diallyl trisulfide results in decreased expression of BID protein	decreases^expression	22578287
35	2050-87-5	BIRC2	Homo sapiens	diallyl trisulfide results in decreased expression of BIRC2 protein	decreases^expression	22578287
36	2050-87-5	BIRC2	Homo sapiens	diallyl trisulfide results in increased expression of BIRC2 protein	increases^expression	21411500
37	2050-87-5	BIRC5	Homo sapiens	diallyl trisulfide results in decreased expression of BIRC5 protein	decreases^expression	23754639
38	2050-87-5	BIRC5	Homo sapiens	diallyl trisulfide results in increased expression of BIRC5 mRNA	increases^expression	21411500
39	2050-87-5	BIRC5	Homo sapiens	diallyl trisulfide results in increased expression of BIRC5 protein	increases^expression	21411500
40	2050-87-5	BMI1	Homo sapiens	diallyl trisulfide affects the expression of BMI1 protein	affects^expression	27129776
41	2050-87-5	BTF3	Homo sapiens	diallyl trisulfide results in increased expression of BTF3 protein	increases^expression	16344271
42	2050-87-5	CALR	Homo sapiens	diallyl trisulfide results in increased expression of CALR protein	increases^expression	19550292
43	2050-87-5	CAPZA1	Homo sapiens	diallyl trisulfide results in decreased expression of CAPZA1 protein	decreases^expression	16344271
44	2050-87-5	CASP3	Homo sapiens	diallyl trisulfide results in increased activity of CASP3 protein	increases^activity	20055834\|21574149\|22595511\|23754639
45	2050-87-5	CASP3	Homo sapiens	diallyl trisulfide results in increased expression of CASP3 mRNA	increases^expression	21574149
46	2050-87-5	CASP3	Rattus norvegicus	diallyl trisulfide inhibits the reaction [Arsenic results in increased activity of CASP3 protein]	decreases^reaction\|increases^activity	24295472
47	2050-87-5	CASP3	Rattus norvegicus	diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]	affects^cotreatment\|decreases^reaction\|increases^expression	25896937
48	2050-87-5	CASP3	Rattus norvegicus	HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25896937
49	2050-87-5	CASP3	Rattus norvegicus	NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]	affects^cotreatment\|decreases^reaction\|increases^expression\|increases^reaction	25896937
50	2050-87-5	CASP8	Homo sapiens	diallyl trisulfide results in increased activity of CASP8 protein	increases^activity	22595511
51	2050-87-5	CASP9	Homo sapiens	diallyl trisulfide results in increased activity of CASP9 protein	increases^activity	22595511
52	2050-87-5	CAT	Rattus norvegicus	diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of CAT protein]	decreases^activity\|decreases^reaction	24295472
53	2050-87-5	CAV1	Homo sapiens	diallyl trisulfide promotes the reaction [NOS3 protein binds to CAV1 protein]	affects^binding\|increases^reaction	20229525
54	2050-87-5	CCNB1	Homo sapiens	diallyl trisulfide promotes the reaction [CDK1 protein binds to CCNB1 protein]	affects^binding\|increases^reaction	20143254
55	2050-87-5	CCNB1	Homo sapiens	diallyl trisulfide results in decreased activity of [CDK1 protein binds to CCNB1 protein]	affects^binding\|decreases^activity	20143254
56	2050-87-5	CCNB1	Homo sapiens	diallyl trisulfide results in increased expression of CCNB1 protein	increases^expression	19823037\|24415872
57	2050-87-5	CCND1	Homo sapiens	diallyl trisulfide results in decreased expression of CCND1 mRNA	decreases^expression	23430952
58	2050-87-5	CCND1	Homo sapiens	diallyl trisulfide results in decreased expression of CCND1 protein	decreases^expression	14693049\|24415872
59	2050-87-5	CCND1	Homo sapiens	diallyl trisulfide results in increased expression of CCND1 mRNA	increases^expression	19823037
60	2050-87-5	CCND1	Homo sapiens	diallyl trisulfide results in increased expression of CCND1 protein	increases^expression	24415872
61	2050-87-5	CDC25C	Homo sapiens	diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDC25C protein	decreases^expression\|increases^phosphorylation	20143254
62	2050-87-5	CDC25C	Homo sapiens	diallyl trisulfide results in decreased expression of CDC25C protein	decreases^expression	23754639
63	2050-87-5	CDH1	Homo sapiens	diallyl trisulfide results in increased expression of CDH1 protein	increases^expression	23412769
64	2050-87-5	CDH1	Homo sapiens	SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of CDH1 protein]	decreases^reaction\|increases^expression	23412769
65	2050-87-5	CDK1	Homo sapiens	diallyl trisulfide results in decreased expression of and results in increased phosphorylation of CDK1 protein	decreases^expression\|increases^phosphorylation	23754639
66	2050-87-5	CDKN1A	Homo sapiens	diallyl trisulfide results in increased expression of CDKN1A mRNA	increases^expression	16222732\|17937621
67	2050-87-5	CDKN1A	Homo sapiens	diallyl trisulfide results in increased expression of CDKN1A protein	increases^expression	16222732\|23754639\|24415872
68	2050-87-5	CDKN1B	Homo sapiens	diallyl trisulfide results in increased expression of CDKN1B protein	increases^expression	14693049
69	2050-87-5	CEBPA	Mus musculus	diallyl trisulfide results in decreased expression of CEBPA mRNA	decreases^expression	22137902
70	2050-87-5	CEBPA	Mus musculus	diallyl trisulfide results in decreased expression of CEBPA protein	decreases^expression	22137902
71	2050-87-5	CEBPA	Mus musculus	diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]	affects^cotreatment\|decreases^expression	22137902
72	2050-87-5	CEBPA	Mus musculus	[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in decreased expression of FASN	affects^cotreatment\|decreases^expression	22137902
73	2050-87-5	CEBPA	Mus musculus	[diallyl trisulfide results in decreased expression of [CEBPA protein co-treated with CEBPB protein co-treated with PPARG protein]] which results in increased abundance of Lipids	affects^cotreatment\|decreases^expression\|increases^abundance	22137902
74	2050-87-5	CEBPB	Mus musculus	diallyl trisulfide results in decreased expression of CEBPB mRNA	decreases^expression	22137902
75	2050-87-5	CEBPB	Mus musculus	diallyl trisulfide results in decreased expression of CEBPB protein	decreases^expression	22137902
76	2050-87-5	CFL1	Homo sapiens	diallyl trisulfide results in decreased expression of CFL1 protein	decreases^expression	16344271
77	2050-87-5	CFLAR	Homo sapiens	diallyl trisulfide results in decreased expression of CFLAR protein	decreases^expression	25205294
78	2050-87-5	CLDN1	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN1 mRNA	decreases^expression	24084732
79	2050-87-5	CLDN1	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN1 protein	decreases^expression	24084732
80	2050-87-5	CLDN2	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN2 mRNA	decreases^expression	24084732
81	2050-87-5	CLDN2	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN2 protein	decreases^expression	24084732
82	2050-87-5	CLDN3	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN3 mRNA	decreases^expression	24084732
83	2050-87-5	CLDN3	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN3 protein	decreases^expression	24084732
84	2050-87-5	CLDN4	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN4 mRNA	decreases^expression	24084732
85	2050-87-5	CLDN4	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN4 protein	decreases^expression	24084732
86	2050-87-5	CLDN5	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN5 mRNA	decreases^expression	24084732
87	2050-87-5	CLDN5	Homo sapiens	diallyl trisulfide results in decreased expression of CLDN5 protein	decreases^expression	24084732
88	2050-87-5	CSTB	Homo sapiens	diallyl trisulfide results in decreased expression of CSTB protein	decreases^expression	16344271
89	2050-87-5	CUL3	Rattus norvegicus	diallyl trisulfide results in decreased expression of CUL3 protein	decreases^expression	23453443
90	2050-87-5	CYP1A1	Rattus norvegicus	diallyl trisulfide promotes the reaction [n-hexane results in increased expression of and results in increased activity of CYP1A1 protein]	increases^activity\|increases^expression\|increases^reaction	28115069
91	2050-87-5	CYP1A2	Rattus norvegicus	diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of CYP1A2 protein]	decreases^reaction\|increases^expression	28115069
92	2050-87-5	CYP2B1	Rattus norvegicus	diallyl trisulfide inhibits the reaction [n-hexane results in increased activity of CYP2B1 protein]	decreases^reaction\|increases^activity	28115069
93	2050-87-5	CYP2E1	Rattus norvegicus	diallyl trisulfide inhibits the reaction [n-hexane results in increased expression of and results in increased activity of CYP2E1 protein]	decreases^reaction\|increases^activity\|increases^expression	28115069
94	2050-87-5	CYP2E1	Rattus norvegicus	diallyl trisulfide results in decreased expression of CYP2E1 protein	decreases^expression	28115069
95	2050-87-5	CYP7A1	Homo sapiens	diallyl trisulfide results in decreased expression of CYP7A1 mRNA	decreases^expression	16382202
96	2050-87-5	DACH1	Homo sapiens	diallyl trisulfide results in increased expression of DACH1 mRNA	increases^expression	27129776
97	2050-87-5	DACH1	Homo sapiens	FOXQ1 protein inhibits the reaction [diallyl trisulfide results in increased expression of DACH1 mRNA]	decreases^reaction\|increases^expression	27129776
98	2050-87-5	DDT	Homo sapiens	diallyl trisulfide results in decreased expression of DDT protein	decreases^expression	16344271
99	2050-87-5	DNAJC27	Homo sapiens	diallyl trisulfide results in decreased expression of DNAJC27 protein	decreases^expression	19550292
100	2050-87-5	DYNLRB1	Homo sapiens	diallyl trisulfide results in decreased expression of DYNLRB1 protein	decreases^expression	19550292
101	2050-87-5	EGFR	Homo sapiens	diallyl trisulfide results in decreased expression of EGFR protein	decreases^expression	23754639
102	2050-87-5	EIF4H	Homo sapiens	diallyl trisulfide results in decreased expression of EIF4H protein	decreases^expression	16344271
103	2050-87-5	ENO1	Homo sapiens	diallyl trisulfide results in increased expression of ENO1 protein	increases^expression	16344271
104	2050-87-5	EPHX1	Rattus norvegicus	diallyl trisulfide results in increased expression of EPHX1 mRNA	increases^expression	20650352
105	2050-87-5	FAS	Homo sapiens	diallyl trisulfide results in increased expression of FAS mRNA	increases^expression	19823037
106	2050-87-5	FAS	Homo sapiens	diallyl trisulfide results in increased expression of FAS protein	increases^expression	24415872
107	2050-87-5	FOXP3	Mus musculus	diallyl trisulfide results in decreased expression of FOXP3 mRNA	decreases^expression	20979868
108	2050-87-5	FOXQ1	Homo sapiens	diallyl trisulfide results in decreased expression of and affects the localization of FOXQ1 protein	affects^localization\|decreases^expression	27129776
109	2050-87-5	FOXQ1	Homo sapiens	diallyl trisulfide results in decreased expression of FOXQ1 mRNA	decreases^expression	27129776
110	2050-87-5	FOXQ1	Homo sapiens	FOXQ1 protein inhibits the reaction [diallyl trisulfide results in decreased expression of MYC mRNA]	decreases^expression\|decreases^reaction	27129776
111	2050-87-5	FTH1	Homo sapiens	benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein]	decreases^expression\|decreases^reaction\|increases^degradation	16707465
112	2050-87-5	FTH1	Homo sapiens	diallyl trisulfide results in increased degradation of and results in decreased expression of FTH1 protein	decreases^expression\|increases^degradation	16707465
113	2050-87-5	FTL	Homo sapiens	benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein]	decreases^expression\|decreases^reaction\|increases^degradation	16707465
114	2050-87-5	FTL	Homo sapiens	diallyl trisulfide results in increased degradation of and results in decreased expression of FTL protein	decreases^expression\|increases^degradation	16707465
115	2050-87-5	FTMT	Homo sapiens	diallyl trisulfide results in decreased expression of FTMT protein	decreases^expression	21616139
116	2050-87-5	FTMT	Homo sapiens	[diallyl trisulfide results in decreased expression of FTMT protein] which results in increased abundance of Iron	decreases^expression\|increases^abundance	21616139
117	2050-87-5	FTMT	Homo sapiens	SHC1 protein affects the reaction [diallyl trisulfide results in decreased expression of FTMT protein]	affects^reaction\|decreases^expression	21616139
118	2050-87-5	FUBP1	Homo sapiens	diallyl trisulfide results in increased expression of FUBP1 protein	increases^expression	16344271
119	2050-87-5	GADD45A	Homo sapiens	diallyl trisulfide results in increased expression of GADD45A mRNA	increases^expression	17937621
120	2050-87-5	GAPDH	Homo sapiens	diallyl trisulfide results in decreased expression of GAPDH protein	decreases^expression	16344271
121	2050-87-5	GSK3B	Rattus norvegicus	diallyl trisulfide results in decreased expression of GSK3B protein	decreases^expression	23453443
122	2050-87-5	GSTA5	Rattus norvegicus	diallyl trisulfide results in increased expression of GSTA5 mRNA	increases^expression	20650352
123	2050-87-5	GSTP1	Homo sapiens	diallyl trisulfide results in decreased expression of GSTP1 mRNA	decreases^expression	16344271
124	2050-87-5	GSTP1	Homo sapiens	diallyl trisulfide results in decreased expression of GSTP1 protein	decreases^expression	16344271
125	2050-87-5	GSTP1	Rattus norvegicus	diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]	affects^binding\|increases^reaction	20237067
126	2050-87-5	GSTP1	Rattus norvegicus	[diallyl trisulfide promotes the reaction [JUN protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA	affects^binding\|increases^expression\|increases^reaction	20237067
127	2050-87-5	GSTP1	Rattus norvegicus	diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]	affects^binding\|increases^reaction	20237067
128	2050-87-5	GSTP1	Rattus norvegicus	[diallyl trisulfide promotes the reaction [NFE2L2 protein binds to GSTP1 enhancer]] which results in increased expression of GSTP1 mRNA	affects^binding\|increases^expression\|increases^reaction	20237067
129	2050-87-5	GSTP1	Rattus norvegicus	diallyl trisulfide results in increased expression of and results in increased activity of GSTP1 protein	increases^activity\|increases^expression	20237067
130	2050-87-5	GSTP1	Rattus norvegicus	diallyl trisulfide results in increased expression of GSTP1 mRNA	increases^expression	20237067
131	2050-87-5	HES1	Homo sapiens	diallyl trisulfide results in decreased expression of HES1 mRNA	decreases^expression	23430952
132	2050-87-5	HEY1	Homo sapiens	diallyl trisulfide results in decreased expression of HEY1 mRNA	decreases^expression	23430952
133	2050-87-5	HEY2	Homo sapiens	diallyl trisulfide results in decreased expression of HEY2 mRNA	decreases^expression	23430952
134	2050-87-5	HIST1H2BM	Homo sapiens	diallyl trisulfide results in decreased expression of HIST1H2BM protein	decreases^expression	16344271
135	2050-87-5	HMOX1	Homo sapiens	Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	24489685
136	2050-87-5	HMOX1	Homo sapiens	diallyl trisulfide results in increased expression of HMOX1 mRNA	increases^expression	24489685
137	2050-87-5	HMOX1	Homo sapiens	diallyl trisulfide results in increased expression of HMOX1 protein	increases^expression	23412769\|24489685
138	2050-87-5	HMOX1	Homo sapiens	Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	24489685
139	2050-87-5	HMOX1	Homo sapiens	NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	24489685
140	2050-87-5	HMOX1	Homo sapiens	SOD2 protein inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	23412769
141	2050-87-5	HMOX1	Mus musculus	NFE2L2 gene mutant form inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	decreases^reaction\|increases^expression	24489685
142	2050-87-5	HMOX1	Rattus norvegicus	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein]	affects^cotreatment\|decreases^reaction\|increases^expression	23453443
143	2050-87-5	HMOX1	Rattus norvegicus	[diallyl trisulfide co-treated with Glucose] results in increased expression of HMOX1 protein	affects^cotreatment\|increases^expression	23453443
144	2050-87-5	HMOX1	Rattus norvegicus	diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]	decreases^expression\|decreases^reaction	23453443
145	2050-87-5	HMOX1	Rattus norvegicus	NFE2L2 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	increases^expression\|increases^reaction	25896937
146	2050-87-5	HMOX1	Rattus norvegicus	PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]	increases^expression\|increases^reaction	25896937
147	2050-87-5	HNF4A	Homo sapiens	diallyl trisulfide results in increased expression of HNF4A mRNA	increases^expression	16382202
148	2050-87-5	HNRNPA2B1	Homo sapiens	diallyl trisulfide results in decreased expression of HNRNPA2B1 protein	decreases^expression	16344271
149	2050-87-5	HNRNPDL	Homo sapiens	diallyl trisulfide results in increased expression of HNRNPDL protein	increases^expression	16344271
150	2050-87-5	HNRNPH1	Homo sapiens	diallyl trisulfide results in increased expression of HNRNPH1 protein	increases^expression	16344271
151	2050-87-5	HSPA5	Homo sapiens	diallyl trisulfide results in decreased expression of HSPA5 protein	decreases^expression	19550292
152	2050-87-5	HSPA8	Homo sapiens	diallyl trisulfide results in decreased expression of HSPA8 protein	decreases^expression	19550292
153	2050-87-5	HSPA9	Homo sapiens	diallyl trisulfide results in decreased expression of HSPA9 protein	decreases^expression	19550292
154	2050-87-5	HSPD1	Homo sapiens	diallyl trisulfide results in decreased expression of HSPD1 protein	decreases^expression	19550292
155	2050-87-5	HYOU1	Homo sapiens	diallyl trisulfide results in decreased expression of HYOU1 protein	decreases^expression	19550292
156	2050-87-5	IL10	Mus musculus	diallyl trisulfide results in decreased expression of and results in decreased secretion of IL10 protein	decreases^expression\|decreases^secretion	20979868
157	2050-87-5	IL1B	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]	decreases^reaction\|increases^expression\|increases^secretion	25500681
158	2050-87-5	IL1B	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]	decreases^reaction\|increases^expression	25500681
159	2050-87-5	IL1B	Mus musculus	[ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25500681
160	2050-87-5	INA	Homo sapiens	diallyl trisulfide results in increased expression of INA protein	increases^expression	19550292
161	2050-87-5	JUN	Rattus norvegicus	diallyl trisulfide results in increased activity of JUN protein	increases^activity	20237067
162	2050-87-5	JUN	Rattus norvegicus	diallyl trisulfide results in increased expression of JUN protein	increases^expression	20237067
163	2050-87-5	KCNA5	Homo sapiens	diallyl trisulfide results in decreased activity of KCNA5 protein	decreases^activity	23272117
164	2050-87-5	KCND3	Homo sapiens	diallyl trisulfide binds to and results in decreased activity of KCND3 protein	affects^binding\|decreases^activity	23272117
165	2050-87-5	KCNH2	Homo sapiens	diallyl trisulfide results in decreased activity of KCNH2 protein	decreases^activity	23272117
166	2050-87-5	KCNH2	Homo sapiens	diallyl trisulfide results in decreased expression of and results in decreased activity of KCNH2 protein	decreases^activity\|decreases^expression	24504171
167	2050-87-5	KEAP1	Homo sapiens	diallyl trisulfide binds to KEAP1 protein	affects^binding	24489685
168	2050-87-5	KEAP1	Rattus norvegicus	diallyl trisulfide results in decreased expression of KEAP1 protein	decreases^expression	23453443
169	2050-87-5	KIT	Homo sapiens	diallyl trisulfide results in increased expression of KIT protein	increases^expression	23663050
170	2050-87-5	KRT10	Homo sapiens	diallyl trisulfide results in increased expression of KRT10 protein	increases^expression	19550292
171	2050-87-5	KRT8	Homo sapiens	diallyl trisulfide results in decreased expression of KRT8 protein	decreases^expression	16344271
172	2050-87-5	MAP2K7	Homo sapiens	diallyl trisulfide affects the expression of MAP2K7 protein	affects^expression	21695758
173	2050-87-5	MAP3K3	Homo sapiens	diallyl trisulfide affects the expression of MAP3K3 protein	affects^expression	21695758
174	2050-87-5	MAPK1	Homo sapiens	diallyl trisulfide results in decreased expression of MAPK1 protein	decreases^expression	21695758
175	2050-87-5	MAPK3	Homo sapiens	diallyl trisulfide results in decreased expression of MAPK3 protein	decreases^expression	21695758
176	2050-87-5	MDM2	Homo sapiens	diallyl trisulfide results in decreased expression of MDM2 protein	decreases^expression	24415872
177	2050-87-5	MIR143	Homo sapiens	diallyl trisulfide results in increased expression of MIR143 mRNA	increases^expression	23430952
178	2050-87-5	MIR145	Homo sapiens	diallyl trisulfide results in increased expression of MIR145 mRNA	increases^expression	23430952
179	2050-87-5	MIR200B	Homo sapiens	diallyl trisulfide results in increased expression of MIR200B mRNA	increases^expression	23430952
180	2050-87-5	MIR200C	Homo sapiens	diallyl trisulfide results in increased expression of MIR200C mRNA	increases^expression	23430952
181	2050-87-5	MIR21	Homo sapiens	diallyl trisulfide results in decreased expression of MIR21 mRNA	decreases^expression	23430952
182	2050-87-5	MIR221	Homo sapiens	diallyl trisulfide results in decreased expression of MIR221 mRNA	decreases^expression	23663050
183	2050-87-5	MMP2	Homo sapiens	diallyl trisulfide results in decreased activity of MMP2 protein	decreases^activity	24084732
184	2050-87-5	MMP2	Homo sapiens	diallyl trisulfide results in decreased expression of and results in decreased activity of MMP2 protein	decreases^activity\|decreases^expression	23430952
185	2050-87-5	MMP2	Homo sapiens	diallyl trisulfide results in decreased expression of MMP2 mRNA	decreases^expression	23430952\|24084732\|25927362
186	2050-87-5	MMP2	Homo sapiens	diallyl trisulfide results in decreased expression of MMP2 protein	decreases^expression	21695758\|25927362
187	2050-87-5	MMP2	Homo sapiens	NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein]	decreases^activity\|increases^reaction	23430952
188	2050-87-5	MMP7	Homo sapiens	diallyl trisulfide results in decreased expression of MMP7 protein	decreases^expression	21695758
189	2050-87-5	MMP9	Homo sapiens	diallyl trisulfide affects the expression of MMP9 protein	affects^expression	21695758
190	2050-87-5	MMP9	Homo sapiens	diallyl trisulfide results in decreased activity of MMP9 protein	decreases^activity	24084732
191	2050-87-5	MMP9	Homo sapiens	diallyl trisulfide results in decreased expression of and results in decreased activity of MMP9 protein	decreases^activity\|decreases^expression	23430952
192	2050-87-5	MMP9	Homo sapiens	diallyl trisulfide results in decreased expression of MMP9 mRNA	decreases^expression	23430952\|24084732\|25927362
193	2050-87-5	MMP9	Homo sapiens	diallyl trisulfide results in decreased expression of MMP9 protein	decreases^expression	25927362
194	2050-87-5	MMP9	Homo sapiens	NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP9 protein]	decreases^activity\|increases^reaction	23430952
195	2050-87-5	MTOR	Homo sapiens	diallyl trisulfide results in decreased expression of MTOR protein	decreases^expression	23754639
196	2050-87-5	MYC	Homo sapiens	diallyl trisulfide results in decreased expression of MYC mRNA	decreases^expression	27129776
197	2050-87-5	MYC	Homo sapiens	diallyl trisulfide results in decreased expression of MYC protein	decreases^expression	23754639
198	2050-87-5	MYD88	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein]	decreases^reaction\|increases^expression	25500681
199	2050-87-5	NDRG1	Homo sapiens	diallyl trisulfide results in increased expression of NDRG1 mRNA	increases^expression	17937621
200	2050-87-5	NFE2L2	Homo sapiens	diallyl trisulfide results in increased expression of and affects the localization of NFE2L2 protein	affects^localization\|increases^expression	24489685
201	2050-87-5	NFE2L2	Homo sapiens	NFE2L2 mutant form inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]	decreases^reaction\|increases^expression	24489685
202	2050-87-5	NFE2L2	Rattus norvegicus	diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]	decreases^expression\|decreases^reaction	23453443
203	2050-87-5	NFE2L2	Rattus norvegicus	diallyl trisulfide promotes the reaction [Glucose results in increased expression of and affects the localization of NFE2L2 protein]	affects^localization\|increases^expression\|increases^reaction	23453443
204	2050-87-5	NFE2L2	Rattus norvegicus	diallyl trisulfide results in increased activity of NFE2L2 protein	increases^activity	20237067
205	2050-87-5	NFE2L2	Rattus norvegicus	diallyl trisulfide results in increased expression of NFE2L2 mRNA	increases^expression	18768114
206	2050-87-5	NFE2L2	Rattus norvegicus	diallyl trisulfide results in increased expression of NFE2L2 protein	increases^expression	20237067\|23453443
207	2050-87-5	NFE2L2	Rattus norvegicus	PIK3R1 protein promotes the reaction [diallyl trisulfide results in increased expression of NFE2L2 protein]	increases^expression\|increases^reaction	25896937
208	2050-87-5	NFKBIA	Homo sapiens	diallyl trisulfide results in increased expression of NFKBIA mRNA	increases^expression	24788927
209	2050-87-5	NFKBIA	Homo sapiens	diallyl trisulfide results in increased expression of NFKBIA protein	increases^expression	24788927
210	2050-87-5	NOS2	Homo sapiens	diallyl trisulfide affects the expression of NOS2 protein	affects^expression	21695758
211	2050-87-5	NOS2	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]	decreases^reaction\|increases^expression	25500681
212	2050-87-5	NOS2	Mus musculus	ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]	decreases^reaction\|increases^expression\|increases^reaction	25500681
213	2050-87-5	NOS3	Homo sapiens	diallyl trisulfide results in increased expression of NOS3 protein	increases^expression	20229525
214	2050-87-5	NOTCH1	Homo sapiens	diallyl trisulfide results in decreased expression of NOTCH1 mRNA	decreases^expression	23430952
215	2050-87-5	NOTCH1	Homo sapiens	diallyl trisulfide results in decreased expression of NOTCH1 protein	decreases^expression	23430952
216	2050-87-5	NQO1	Homo sapiens	Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]	decreases^reaction\|increases^expression	24489685
217	2050-87-5	NQO1	Homo sapiens	diallyl trisulfide results in increased expression of NQO1 mRNA	increases^expression	24489685
218	2050-87-5	NQO1	Homo sapiens	diallyl trisulfide results in increased expression of NQO1 protein	increases^expression	24489685
219	2050-87-5	NQO1	Homo sapiens	Dithiothreitol inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]	decreases^reaction\|increases^expression	24489685
220	2050-87-5	NUCB1	Homo sapiens	diallyl trisulfide results in decreased expression of NUCB1 protein	decreases^expression	19550292
221	2050-87-5	OGDH	Rattus norvegicus	diallyl trisulfide inhibits the reaction [Arsenic results in decreased activity of OGDH protein]	decreases^activity\|decreases^reaction	24295472
222	2050-87-5	PGK1	Homo sapiens	diallyl trisulfide results in increased expression of PGK1 protein	increases^expression	16344271
223	2050-87-5	PLAUR	Homo sapiens	diallyl trisulfide affects the expression of PLAUR protein	affects^expression	27129776
224	2050-87-5	PLIN3	Homo sapiens	diallyl trisulfide results in increased expression of PLIN3 protein	increases^expression	16344271
225	2050-87-5	PPARA	Homo sapiens	diallyl trisulfide results in increased expression of PPARA mRNA	increases^expression	16382202
226	2050-87-5	PPARG	Mus musculus	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide results in decreased expression of and results in decreased activity of PPARG protein]	decreases^activity\|decreases^expression\|decreases^reaction	22137902
227	2050-87-5	PPARG	Mus musculus	diallyl trisulfide results in decreased activity of PPARG protein	decreases^activity	22137902
228	2050-87-5	PPARG	Mus musculus	diallyl trisulfide results in decreased expression of PPARG mRNA	decreases^expression	22137902
229	2050-87-5	PPARG	Mus musculus	diallyl trisulfide results in decreased expression of PPARG protein	decreases^expression	22137902
230	2050-87-5	PSMA1	Homo sapiens	diallyl trisulfide results in decreased expression of PSMA1 protein	decreases^expression	19550292
231	2050-87-5	PTGS2	Homo sapiens	diallyl trisulfide affects the expression of PTGS2 protein	affects^expression	21695758
232	2050-87-5	PTGS2	Homo sapiens	diallyl trisulfide results in decreased expression of PTGS2 mRNA	decreases^expression	15523159
233	2050-87-5	PTGS2	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]	decreases^reaction\|increases^expression	25500681
234	2050-87-5	PTGS2	Mus musculus	ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate promotes the reaction [diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]]	decreases^reaction\|increases^expression\|increases^reaction	25500681
235	2050-87-5	RELA	Homo sapiens	diallyl trisulfide results in decreased expression of RELA mRNA	decreases^expression	24788927
236	2050-87-5	RELA	Homo sapiens	diallyl trisulfide results in decreased expression of RELA protein	decreases^expression	24788927
237	2050-87-5	S100A11	Homo sapiens	diallyl trisulfide results in increased expression of S100A11 protein	increases^expression	16344271
238	2050-87-5	SHC1	Homo sapiens	SHC1 protein affects the susceptibility to diallyl trisulfide	affects^response to substance	21616139
239	2050-87-5	SHC1	Homo sapiens	SHC1 protein modified form results in decreased susceptibility to diallyl trisulfide	decreases^response to substance	22020565
240	2050-87-5	SOD1	Rattus norvegicus	diallyl trisulfide results in increased expression of SOD1 protein	increases^expression	23453443
241	2050-87-5	SOD2	Homo sapiens	SOD2 protein inhibits the reaction [diallyl trisulfide results in decreased expression of VIM protein]	decreases^expression\|decreases^reaction	23412769
242	2050-87-5	SOD2	Rattus norvegicus	diallyl trisulfide results in increased expression of SOD2 protein	increases^expression	23453443
243	2050-87-5	SRSF1	Homo sapiens	diallyl trisulfide results in increased expression of SRSF1 protein	increases^expression	16344271
244	2050-87-5	TAGLN2	Homo sapiens	diallyl trisulfide results in increased expression of TAGLN2 protein	increases^expression	16344271
245	2050-87-5	TGFB1	Mus musculus	diallyl trisulfide results in decreased expression of and results in decreased secretion of TGFB1 protein	decreases^expression\|decreases^secretion	20979868
246	2050-87-5	TIMP1	Homo sapiens	diallyl trisulfide results in increased expression of TIMP1 mRNA	increases^expression	24084732
247	2050-87-5	TIMP1	Homo sapiens	diallyl trisulfide results in increased expression of TIMP1 protein	increases^expression	24084732
248	2050-87-5	TIMP2	Homo sapiens	diallyl trisulfide results in increased expression of TIMP2 mRNA	increases^expression	24084732
249	2050-87-5	TIMP2	Homo sapiens	diallyl trisulfide results in increased expression of TIMP2 protein	increases^expression	24084732
250	2050-87-5	TLR4	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]	decreases^reaction\|increases^expression	25500681
251	2050-87-5	TNF	Homo sapiens	diallyl trisulfide results in decreased expression of TNF mRNA	decreases^expression	16110831
252	2050-87-5	TNF	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]	decreases^reaction\|increases^expression\|increases^secretion	25500681
253	2050-87-5	TNF	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]	decreases^reaction\|increases^expression	17448272\|25500681
254	2050-87-5	TNF	Mus musculus	diallyl trisulfide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]	decreases^reaction\|increases^expression	17448272
255	2050-87-5	TNF	Mus musculus	[ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate co-treated with diallyl trisulfide] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]	affects^cotreatment\|decreases^reaction\|increases^expression	25500681
256	2050-87-5	TP53	Homo sapiens	diallyl trisulfide results in increased expression of and affects the localization of TP53 protein	affects^localization\|increases^expression	19823037
257	2050-87-5	TP53	Homo sapiens	diallyl trisulfide results in increased expression of TP53 mRNA	increases^expression	19823037\|24415872
258	2050-87-5	TP53	Homo sapiens	diallyl trisulfide results in increased expression of TP53 protein	increases^expression	23754639
259	2050-87-5	TPT1	Homo sapiens	diallyl trisulfide results in decreased expression of TPT1 protein	decreases^expression	16344271
260	2050-87-5	UCHL1	Homo sapiens	diallyl trisulfide results in decreased expression of UCHL1 protein	decreases^expression	19550292
261	2050-87-5	UGT1A1	Rattus norvegicus	diallyl trisulfide results in increased expression of UGT1A1 mRNA	increases^expression	20650352
262	2050-87-5	VDAC1	Homo sapiens	diallyl trisulfide results in decreased expression of VDAC1 protein	decreases^expression	16344271
263	2050-87-5	VDAC2	Homo sapiens	diallyl trisulfide results in decreased expression of VDAC2 protein	decreases^expression	16344271
264	2050-87-5	VEGFA	Homo sapiens	diallyl trisulfide results in decreased expression of and results in decreased secretion of VEGFA protein	decreases^expression\|decreases^secretion	23430952
265	2050-87-5	VEGFA	Homo sapiens	diallyl trisulfide results in decreased expression of VEGFA mRNA	decreases^expression	23430952
266	2050-87-5	VEGFA	Homo sapiens	diallyl trisulfide results in decreased expression of VEGFA protein	decreases^expression	23754639
267	2050-87-5	VIM	Homo sapiens	diallyl trisulfide results in decreased expression of VIM protein	decreases^expression	19550292\|23412769
268	2050-87-5	XIAP	Homo sapiens	Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]	decreases^expression\|decreases^reaction	22578287
269	2050-87-5	XIAP	Homo sapiens	benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]	decreases^expression\|decreases^reaction	21411500
270	2050-87-5	XIAP	Homo sapiens	diallyl trisulfide results in decreased expression of XIAP protein	decreases^expression	21411500\|22578287\|25205294
271	2050-87-5	XIAP	Homo sapiens	XIAP protein results in decreased susceptibility to diallyl trisulfide	decreases^response to substance	21411500

Serial No.	Activity Name	Details	References (PubMed)	Other details EPA (U.S)	Clinical Trials (U.S. NIH)

Plant Variety and Essential oils

Serial No.	Plant Name	Variety Name	Essential Oil	Compound Percentage
1	Garlic		Allium sativum essential oil
2	Welsh onion		Allium fistulosum essential oil

Print Back

Compound Image

2D Structure

Download

Download Sdf File Download PDB File Download MOL File

View Similar Structures (External DB)

AromaDb: A Database of Plant's Aroma Molecules

AROMA: A Database of Plant's Aroma Molecules